background:breast cancer remains the most common and second lethal cancer in females. her-2/neu is one of the most important amplified oncogene in breast cancer. the amplification of her-2 is correlated with decreased survival, metastasis, and early recurrence.  the amplification of her-2/neu gene and synthesis of the protein are reported in 10%-34% of breast cancer cases associated with tumor ...

background the incidence rate of gastric cancer in western countries has shown a remarkable decline in the recent years while it is still the most common cancer among males in iran. the proto-oncogene myc, located at 8q24.1, regulates almost 15% of human genes and is activated in 20% of all tumors. the amplification of myc and overexpression of its protein product are observed in 15 - 30% of ga...

in this study, doxycycline hyclate release behavior from in situ forming drug delivery systems investigated. these systems based on poly()lactide-co-glycolide)(50:50 dissolved in n-methyl-2-pyrrolidone that were evaluated in different concentrations. these systems are useful for local treatment of periodontal diseases. uv spectroscopy is used to determine drug concentration in release medium. a...

In studying of the in situ gravitational concentration process part feature for placer, the technological ability to transform the in situ massif placer structure is evident. The two main processes involved in altering the massif in situ have been examined and outlined in detail. The in situ disintegration of massif material results in a new massif gravitational stratification structure. Regula...

soil affected by salt (nacl) is a major problem worldwide and in areas with potential agriculture; lands in many countries are not enough to support crop production. the development of salt tolerant cultivars would be enhanced by better understanding of the genetic control of tolerance to salt stress. a new cereal, tritipyrum, a range of amphiploids between triticum spp. and thinopyrum spp....

natural radionuclides present in soil as well as certain anthropogenic radionuclides released to the environment are the major contributors to terrestrial outdoor exposures. in the assessment of human exposures from environmental radioactivity, besides the conventional method of soil and vegetation sampling combined with laboratory based analyses of environmental media, the other choice would b...

the simultaneous flow of oil and water in porous media is described by relative permeability curves, mainly derived from laboratory experiments. relative permeability is of paramount importance in predicting reservoir production performance and drive mechanisms and its value depends largely on the volume fraction of fluids present in the test samples. nowadays x-ray scanners are one of the most...