نتایج جستجو برای: in vitro susceptibility testing
تعداد نتایج: 17047945 فیلتر نتایج به سال:
In general, methods to test the susceptibility of fungi to antifungal drugs require standardized techniques, but so far there is no methodology that is widely applicable to dermatophytes. Here we introduced modifications to the protocols from documents of the National Committee for Clinical Laboratory Standards (CLSI) M38-A and the Antifungal Susceptibility Testing Subcommittee of the European ...
The treatment of vulvovaginal candidiasis (VVC) due to Candida glabrata is challenging, with limited therapeutic options. Unexplained disappointing clinical efficacy has been reported with systemic and topical azole antifungal agents in spite of in vitro susceptibility. Given that the vaginal pH of patients with VVC is unchanged at 4 to 4.5, we studied the effect of pH on the in vitro activity ...
OBJECTIVES A patient with Candida albicans thrush and oesophagitis was treated with high doses of caspofungin but treatment eventually failed. Four C. albicans isolates were serially recovered before and after caspofungin treatment. A microbiological study was performed to characterize these four isolates. METHODS In vitro antifungal susceptibility testing was performed by the EUCAST referenc...
Received: 14 April, 2009 Accepted: 21 Oct, 2009 Abstract Background & Aims: Antimicrobial resistance among bacterial pathogens is a worldwide problem. The selection of initial treatment is made on an empiric basis and susceptibility testing is important to modify empirical therapy, especially for treatment of common bacterial pathogens. The aim of the present study was to determine the antimi...
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A novel therapeutic approach for Nocardia infections is presented. We report the successful treatment of lymphocutaneous nocardiosis with a three-drug combination in an immunocompromised patient with in vitro susceptibility testing used to guide therapy. New therapeutic options are required in some patients due to their failure to respond to the treatment of choice, trimethoprim-sulfamethoxazol...
The availability of standardized antifungal susceptibility testing methodologies as well as the definition of interpretative breakpoints have made possible the establishment of useful correlations between in vitro testing data and clinical results with antifungal drugs such as fluconazole and itraconazole in patients with oropharyngeal candidiasis. The results obtained in these studies, however...
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