We report here the effect of increased amount a water-immiscible ionic liquid (IL), 1-butyl-1-methylpyrrolidinium bis(trifluoromethanesulfonyl)imide (P14-TFSI), enhancing production paclitaxel with in situ extraction from an aqueous medium plant cell culture. The productivity culture including IL 10 vol% was 1.5 times greater than that 2.5 vol%. Moreover, addition elicitor, methyl jasmonate (MJ...