From September 1984 to February 1985 a total of three hundred and five specimens of nasopharyngeal secretion (NPS) were examined by the indirect immuno-fluorescence technique to determine the frequency of infections caused by the respiratory syncytial virus (RSV), influenza A, influenza B and parainfluenza viruses, 1 and 3. The specimens were collected from infants and children less than 5 year...

Important insights into nuclear function would arise if gene loci physically interacting with particular subnuclear domains could be readily identified. Immunofluorescence microscopy combined with fluorescence in situ hybridization (immuno-FISH), the method that would typically be used in such a study, is limited by spatial resolution and requires prior assumptions for selecting genes to probe....

-Selected monoclonal antibodies (McAbs) isolated after immunization of rats with a human colonic carcinoma membrane preparation, have been screened on frozen and paraffin sections of colonic tissue, using immunohistochemical techniques, in order to provide additional information with regard to specificity and crossreactivity with normal tissues. Of 10 McAbs previously shown to bind to a colonic...

europium (eu) doped zno microsphere based nano-sheets were synthesized through hydrothermal method. effects of different concentrations of europium on structural and optical properties of zno nano-sheets were investigated in detail. prepared un-doped and eu-doped zno samples were characterized using x-ray diffraction (xrd), energy dispersive x-ray spectroscopy (edx), scanning electron microscop...

one hundred sera from children 1 - 6 years of age, representative of a large serum collection, were tested for the prevalence of antibodies against different viruses. hemagglutination-inhibition (hi) antibodies were found in 68% for measles; 61 % for rubella; 75'% for influenza a2/hong kong/68, 16% for influenza b/md./59, 0% for group a arboviruses, 10% for group b arboviruses, 3% for phlebotom...

Protein aggregation is phenomenon wherein protein loses its native structure and aggregates due to the adaption of non-native conformation. Amyloid aggregation formed by the accumulation of various proteins causes many diseases in humans and other organisms. Antioxidants can prevent proteins aggregation. Pulicaria undulata  extract along with phenolic compounds can increase protein stability an...

Mycoplasma pneumoniae is a particularly important pathogen that causes community acquired pneumonia in children. In this study, a rapid test was developed to diagnose M. pneumoniae by using a colloidal gold-based immuno-chromatographic assay which targets a region of the P1 gene. 302 specimens were analyzed by the colloidal gold assay in parallel with real-time PCR. Interestingly, the colloidal...

Many drugs and other small molecules used to modulate biological function are amphiphiles that adsorb at the bilayer/solution interface and thereby alter lipid bilayer properties. This is important because membrane proteins are energetically coupled to their host bilayer by hydrophobic interactions. Changes in bilayer properties thus alter membrane protein function, which provides an indirect w...