نتایج جستجو برای: individualized medicine
تعداد نتایج: 265183 فیلتر نتایج به سال:
Over the past decade, theragnostic radiopharmaceuticals have been used in nuclear medicine for both diagnosis and treatment of various tumors. In this review, we carried out a literature search to investigate explain role radiotracers approach glioblastoma multiform (GBM). We primarily focused on basic rather common positron emotion tomography (PET) these Subsequently, introduced evaluated prec...
Contemporary medicine has been in the process of a paradigm shift. Instead of relatively broad pathological entities, population-based risk assesments, and non-specific "one-size-fits-all" therapies, a new paradigm of predictive, individualized and personalized care and targeted therapy is rolling on the horizon. Person-centered medicine is a term with different meanings which competes in some ...
Warfarin is the most widely used oral anticoagulant in the world for patients with venous thrombosis, pulmonary embolism, chronic atrial fibrillation, and prosthetic heart valves. Approximately 30 genes contribute to therapeutic effects of warfarin, and genetic polymorphisms in these genes may modulate its anticoagulant activity. In contrast to monogenic pharmacogenetic traits, warfarin drug re...
In today's aging society, more people are living with lifestyle-related noncommunicable diseases (NCDs) such as cardiovascular disease, type 2 diabetes, obesity, and cancer. Numerous opinion-leader organizations recommend lifestyle medicine as the first-line approach in NCD prevention and treatment. However, there is a strong need for a personalized approach as "one-size-fits-all" public health...
Establishing Individualized Medicine for Intractable Cancer Based on Clinical Molecular Pathogenesis
The age of genomic medicine is upon us. Sixty years have passed since Watson and Crick’s discovery about the double-helical structure of DNA (Watson and Crick 1953). Ten years have passed since the Human Genome Project’s (HGP) completion (International Human Genome Sequencing Consortium 2004). We now witness the translation of this basic science into direct patient care. With the cost of sequen...
Pharmaco-electroencephalography (Pharmaco-EEG) studies using clinical EEG and quantitative EEG (qEEG) technologies have existed for more than 4 decades. This is a promising area that could improve psychotropic intervention using neurological data. One of the objectives in our clinical practice has been to collect EEG and quantitative EEG (qEEG) data. In the past 5 years, we have identified a su...
The use of pharmacogenomics has become more prevalent over the past several years in treating many disease states. Several cytochrome P450 enzymes play a role in the metabolism of many pain medications including opioids and antidepressants. Noncytochrome P450 enzymes such as methylenetetrahydrofolate reductase (MTHFR) and catechol-O-methyl transferase (COMT) also play a role in the explanation ...
OBJECTIVE To report the design and implementation of the first 3 years of enrollment of the Mayo Clinic Biobank. PATIENTS AND METHODS Preparations for this biobank began with a 4-day Deliberative Community Engagement with local residents to obtain community input into the design and governance of the biobank. Recruitment, which began in April 2009, is ongoing, with a target goal of 50,000. An...
Lower limb lymphedema is one of the common postoperative complications gynecologic malignancies, which brings great physical pain and psychological pressure to patients. In clinical treatment, Western medicine mainly based on conservative drug treatment surgery. Chinese "evidence" has various intervention methods, including internal external application medicine, acupuncture moxibustion, tui-na...
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