نتایج جستجو برای: indoleamine 2

تعداد نتایج: 2526824  

Journal: :Haematologica 2014
Paolo Giannoni Gabriella Pietra Giorgia Travaini Rodolfo Quarto Genti Shyti Roberto Benelli Laura Ottaggio Maria Cristina Mingari Simona Zupo Giovanna Cutrona Ivana Pierri Enrico Balleari Alessandra Pattarozzi Marco Calvaruso Claudio Tripodo Manlio Ferrarini Daniela de Totero

Hepatocyte growth factor, produced by stromal and follicular dendritic cells, and present at high concentrations in the sera of patients with chronic lymphocytic leukemia, prolongs the survival of leukemic B cells by interacting with their receptor, c-MET. It is, however, unknown whether hepatocyte growth factor influences microenvironmental cells, such as nurse-like cells, which deliver surviv...

Journal: :Cancer research 1990
G Werner-Felmayer E R Werner D Fuchs A Hausen G Reibnegger H Wachter

Determination of neopterin [D-erythro-6-(1',2',3'-trihydroxypropyl)pterin] in body fluids is a powerful diagnostic tool in a variety of diseases in which activation of cellular immune mechanisms is involved, such as certain malignancies, allograft rejection, and autoimmune and infectious diseases. In vitro, neopterin is released into the supernatant by peripheral blood-derived monocytes/macroph...

Journal: :The Biochemical journal 2001
S Suzuki S Toné O Takikawa T Kubo I Kohno Y Minatogawa

Indoleamine 2,3-dioxygenase (IDO)-initiated tryptophan degradation in the placenta has been implicated in the prevention of the allogeneic fetus rejection [Munn, Zhou, Attwood, Bondarev, Conway, Marshall, Brown, and Mellor (1998) Science 281, 1191-1193]. To determine how IDO is associated with the development of the fetus and placenta, the time course of IDO expression (tryptophan-degrading act...

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