Diabetic foot ulcers are the consequence of multiple factors including peripheral neuropathy, decreased blood supply, high plantar pressures, etc., and pose a significant risk for morbidity, limb loss and mortality. The critical aspects of the wound healing mechanism and host physiological status in patients with diabetes necessitate the selection of an appropriate treatment strategy based on t...

Background: Foot ulcer is the most common complication that leads to amputation in diabetic patients. Purpose: To study the effect of intermittent pneumatic compression therapy (IPCT) in enhancing healing of chronic diabetic foot ulcer. Methods: Thirty-eight patients (13 men & 25 women) with type II diabetes and foot ulcer grade ІІ according to Wagner classification were recruited to participat...

BACKGROUND Foot ulcers (FU) are a significant complication of diabetes mellitus (DM) and a preceding factor leading to lower extremity amputation. The aim of this study was to evaluate the management of diabetic foot ulcer (DFU) in Babol, north of Iran. METHODS Five hundred twenty cases of diabetic foot ulcer that were hospitalized in two main teaching hospitals of Babol University of Medical...

Objective: The current study was conducted to compare the effect of 150,000 and 300,000 IU of vitamin D on the healing status of diabetic foot ulcer among the patients with diabetes. Materials and Methods: This randomized clinical trial was carried out on 47 patients with diabetic foot ulcer and vitamin deficiency during four weeks follow-up. The patients were randomly assigned into two groups...

Normal subjects and diabetic patients with and without food ulcers have been studied using an apparatus which measures the loads on the foot during walking. Diabetic patients have alterations in loading which show as a lateral shift of the highest maximum load on the forefoot and a decrease in the load carried by the toes. There is a significant progression of these changes between normal subje...

Globally, diabetes mellitus has grown to pandemic proportions, affecting 194 million people worldwide and is expected to increase in prevalence to 344 million by the year 2030 (Wild, et al., 2004). Of these patients, between 2 and 6% will develop a diabetic foot ulcer (DFU) yearly (Ramsey, et al., 1999). The onset of a DFU often precipitates a complex chain of events that may lead to limb loss....