نتایج جستجو برای: infective agents
تعداد نتایج: 374061 فیلتر نتایج به سال:
In 55 instances, a single proprietary (trade) name has been used to market > or = 2 distinct generic anti-infective agents. In some cases, one trade name represents 2 different drugs in the same country--or even marketed by the same manufacturer. Some unrelated drugs and poisonous substances are also manufactured under trade names assigned to anti-infectives. The use of proprietary names in the...
Introduction Heparanase is an endo-b-glucuronidase that cleaves highly potent heparan sulfate (HS) from its proteoglycan, thereby triggering the inflammatory response in [1]. Thus, new anti-infective agents that interact with heparanase may be promising tools for sepsis therapy. As a novel anti-infective agent, peptide 19-2.5 (pep2.5) belongs to the class of synthetic anti-lipopolysaccharide pe...
Program Description With antimicrobial resistance on the rise and very few new pharmaceutical agents in development, a well-managed antimicrobial stewardship program in the hospital becomes the first-line defense against the emergence of resistance and provides not only a cost-containment measure but also ensures the continued efficacy of available antimicrobials. A successful stewardship progr...
A significant number of patients with abdominal infection develop advanced stages of infection and mortality is still above 20%. Failure is multifactorial and is associated with an increase of bacterial resitance, inappropriate empirical treatment, a higher comorbidity of patients and poor source control of infection. These guidelines discuss each of these problems and propose measures to avoid...
Concise guidelines are presented that recommend the method of choice for skin antisepsis before central neuraxial blockade. The Working Party specifically considered the concentration of antiseptic agent to use and its method of application. The advice presented is based on previously published guidelines, laboratory and clinical studies, case reports, and on the known properties of antiseptic ...
Increasing resistance of pathogens to anti-infective drugs is an urgent public health problem that must be addressed through more prudent use of these drugs in human medicine and in animal husbandry, agriculture, and aquaculture.
False-positive blood culture results may lead to prolonged hospitalization, inappropriate antibiotic administration, and increased healthcare costs. We conducted a review of the literature to assess the effect of skin antiseptic agents on the rate of false-positive blood culture results. We found no clear evidence to suggest which antiseptic should be used to prevent false-positive results. Stu...
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