Previous research has documented that body dissatisfaction is positively related to social anxiety. However, little known about the mediating and moderating mechanisms underlying this relation. Based on person-environment interaction theory, study aimed examine chain mediation effect of feeling inferiority family cohesion in relationship between anxiety among adolescents whether process was mod...

Cutis verticis gyrata (CVG) is a skin condition characterized by excessive growth of the skin of the scalp, resulting in furrows and folds which are similar to the gyri of the brain cortex. CVG can be classified into two forms: primary (essential and non-essential) and secondary. We report the case of a 53-year-old male patient with the primary type of CVG. The patient did not present with any ...

AIM We aimed to investigate the non-inferiority of PA21 (sucroferric oxyhydroxide) to sevelamer hydrochloride (sevelamer) in terms of efficacy and safety in Japanese haemodialysis patients with hyperphosphataemia. METHODS In this Phase III, open-label, multicentre study, 213 haemodialysis patients with hyperphosphataemia were randomized to PA21 or sevelamer treatment for 12 weeks. The primary...

PURPOSE The aim of this study was to measure the effect of an iPad-based asynchronous curriculum on emergency medicine resident performance on the in-training exam (ITE). We hypothesized that the implementation of an asynchronous curriculum (replacing 1 hour of weekly didactic time) would result in non-inferior ITE scores compared to the historical scores of residents who had participated in th...

Individuals are recruited during an accrual period of R years (or months or days). They are followed for an additional period of time until a total of T years is reached. Hence, the follow-up period is T-R years. At the end of the study, the non-inferiority logrank test is conducted at significance level α with power 1− β . Under the proportion hazards assumption, the hazard ratio HR = h2 / h1 ...

BACKGROUND Rapid reversal of vitamin K antagonist (VKA)-induced anticoagulation is often necessary for patients needing urgent surgical or invasive procedures. The optimum means of VKA reversal has not been established in comparative clinical trials. We compared the efficacy and safety of four-factor prothrombin complex concentrate (4F-PCC) with that of plasma in VKA-treated patients needing ur...