Inflammatory bowel disease (IBD) is a complex multifactorial disease of unknown etiology. Thus, dozens of different animal models of IBD have been developed in past decades. Animal models of IBD are valuable and indispensable tools that provide a wide range of options for investigating involvement of various factors into the pathogenesis of IBD and to evaluate different therapeutic options. How...

abstract background: inflammatory bowel disease (ibd) is a group of inflammatory conditions of the colon and small intestine that may have critical consequences on patient’s quality of life (qol). many disease-specific qol tools have been developed recently. the mcmaster inflammatory bowel disease questionnaire (ibdq) is one of them. the aim of this study was to translate into persian and evalu...

Pyoderma gangrenosum (PG) is a rare, ulcerating inflammatory skin disease. PG is often associated with systemic diseases, including inflammatory bowel disease (IBD). Herein, we report a case of PG associated with ulcerative colitis successfully treated with infliximab. Our case report supports the efficacy of infliximab for refractory case of PG with IBD.

abstract background and purpose: customer quality (cq) refers to knowledge, attitude, and skills of service-user in treatment process and this study aims to assess it in delivered care to patients with inflammatory bowel disease (ibd) in tabriz city, iran, 2012. materials and methods: this is a cross-sectional investigation in which the target population includes 94 patients with ibd, who had m...

IBD: inflammatory bowel disease PG: pyoderma gangrenosum TNF-a: tumor necrosis factor alpha INTRODUCTION Pyoderma gangrenosum (PG) is a rare infiltrative neutrophilic dermatosis that characteristically presents with painful ulcers with violaceous, undermined borders on the lower extremities and less commonly presents with tender nodules or pustules. Along with erythema nodosum, PG is one of the...

background inflammatory bowel disease (ibd) is a chronic, relapsing, inflammatory disorder of the gastrointestinal tract that includes two entities, crohn`s disease (cd) and ulcerative colitis (uc). as with other complex diseases, both genetic susceptibility and environmental factors play role in the pathogenesis of these diseases. the tumor necrosis factor α (tnf-α) gene is located in the ibd3...

Inflammatory bowel disease (IBD), which includes ulcerative colitis, and Crohn’s disease, is a chronic relapsing-remitting inflammatory state of the gastrointestinal (GI) system. The cause IBD multifactorial, encompassing factors genetics, environment, host immune system, initiating complex interplay maladaptive responses subsequent inflammation. Aberrant are at least in part due to changes com...

'Inflammatory bowel disease' (IBD) sounds like a straightforward term - a disease of inflammation in the bowel. However, the history of IBD reveals a story of a nefariously complex set of idiopathic conditions. IBD defies definition, in part because its pathophysiology is not completely understood. For the same reason and despite substantial advances in research, IBD also defies cure. At best, ...

inflammatory bowel diseases are one of the important reasons of the referral to gi practitioners in our country and ulcerative colitis is the more frequent type of these disease in iran. in this study 200 cases of ulcerative colitis, which has been referred to imam khomeini hospital during that last 5 year, were studied. data was collected using the patient's records and face to face inter...

BACKGROUND Patients with inflammatory bowel disease (IBD) are thought to be at increased risk of venous thromboembolism (TE). However, the extent of this risk is not known. Furthermore, it is not known if this risk is specific for IBD or if it is shared by other chronic inflammatory diseases or other chronic bowel diseases. AIMS To compare the risk of TE in patients with IBD, rheumatoid arthr...