objectives: iron chelators, such as maltol and kojic acid, have antioxidant and anti-inflammatory properties. they may have beneficial effects on inflammatory bowel disease (ibd) because iron can develop and aggravate inflammation in ibd. in the present study, the effect of selected iron chelators and anti-oxidants were evaluated on a model of trinitrobenzene sulfonic acid (tnbs)-induced coliti...

the main inflammatory bowel disorders are including celiac disease (cd), inflammatory bowel diseases (ibd) and irritable bowel syndrome (ibs). celiac disease is a digestive and autoimmune disorder that can damage the small intestine and characterized by a multitude gastrointestinal (gi) and extra gi symptoms. ibd (including ulcerative colitis and crohn’s disease) is a group of inflammatory cond...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: symptoms consistent with irritable bowel syndrome (ibs) are common among patients with inflammatory bowel disease (ibd) in remission phase, and clinicians have difficulties in interpreting such symptoms as an ongoing disease activity or a coexistent ibs. we investigated if the assessment of fecal calprotectin (...

inflammatory bowel disease (ibd) is a chronic relapsing, idiopathic disorder of the gastrointestinal tract of an unknown etiology. ulcerative colitis (uc) and crohn's disease (cd) have become important health problems.â  current medical therapy of ibd has advanced dramatically with the introduction of new biologic therapies in addition to the optimization of conventional therapies that include ...

inflammatory bowel diseases (ibd) were systemic disorders involving many organ systems. besides intestinal manifestations, extra intestinal manifestations (eims) including neurologic complications have been reported among 6%-40% of ibd patients. ulcerative colitis (uc) was a subtype of ibd only affecting the colonic mucosa and sub mucosa. although the eims of uc could affect any organ system, c...

background : ulcerative colitis an inflammatory bowel disease (ibd) and chronically idiopathic immune related that associates with extraintestinal manifestations such as arthritis. despite of the highly specificity ofanti-cyclic citrullinated peptide (ccp) antibodies for rheumatoid arthritis, their role in ibd remains unclear . there are only a few studies on the prevalence of anti-ccp antibodi...

alzheimer's disease (ad) is a chronic neurodegenerative disease that accounts for 60 to 80 percent of all dementia cases. the exact cause of alzheimer`s disease is still unknown, but recent studies suggest neuro-inflammation as an important part of the pathogenesis of the disease. this brings in mind using non-steroidal anti-inflammatory drugs (nsaid) as treatment or prevention of the dise...

Background: Dry Eye Disease (DED) is a prevalent condition that involves instability, increased osmolarity, and inflammation of the tear film ocular surface. Vitamin D known for its anti-inflammatory properties. Association between vitamin deficiency incidence DED has been suggested. However, no study currently exists systematically reviews potential role as treatment DED. Methods: The literatu...

PURPOSE To study the efficacy and incidence of treatment-related side effects of mycophenolate mofetil (MMF) therapy in patients with noninfectious inflammatory eye diseases. METHODS Retrospective cohort study of 27 Chilean patients treated for noninfectious inflammatory eye diseases using MMF therapy over a 10-year period. Main outcome measures were: ability to control ocular inflammation an...