PURPOSE Insulin inhibits glucose release in the liver but increases glucose absorption in muscles. When insulin cannot properly control glucose, it negatively affects glucose metabolism and, furthermore, contributes to the onset of metabolic syndrome and chronic disease. Therefore, this study's goal is to understand the clinical characteristics of hepatic insulin resistance and muscle insulin s...

AimsWe aimed to review insulin dosing recommendations, regulation and its determinants, glycaemic response carbohydrates, the efficacy safety of therapy in different races/ethnicities.MethodsWe searched for articles PubMed Google Scholar databases up 31 March 2021, with following keywords: “ethnicity”, “diabetes”, “insulin”, “history insulin”, “insulin therapy”, “food/rice”, “carbohydrate intak...

OBJECTIVE The purpose of this study was to characterize differences in the acute insulin response to glucose (AIR(g)) relative to insulin sensitivity (S(I)) in black and white premenopausal normoglycemic South African women matched for body fatness. RESEARCH DESIGN AND METHODS Cross-sectional analysis including 57 black and white South African women matched for BMI, S(I), AIR(g), and the disp...

atherosclerosis has serious role in coronary arteries disease,so it is important to establish effective strategies for prevention or even treatment of atherosclerosis. adiponectin, as one of the most abundant adipokines, has insulin sensitivity, anti-inflammatory and anti-atherogenic properties. disturbed adiponectin actions through its receptor, (adipor1 and adipor2) may be involved in atheros...

Background: Type II Diabetes mellitus (T2DM) is a multifactorial disease and a leading cause of premature deaths. Inflammatory cytokines are reported that they have potential to enhance insulin resistance and hence T2DM. Assessment of immunological profile in T2DM patients of Kashmir valley is unclear. So, detection of cytokines is relevant to determine the extent and direction of immune respon...

Although insulin sensitivity is correlated with high blood pressure in adults, it is unclear whether such a relationship exists in children across ethnic groups. Therefore, the aims of the study were to establish (1) if body composition and insulin sensitivity were related to blood pressure in children, and (2) if any differences in blood pressure between white and black children were explained...

1 Postprandial Glucose Fluxes and Insulin Sensitivity during Exercise: 1 A Study in Healthy Individuals 2 3 Michele Schiavon * 4 Ling Hinshaw 5 Ashwini Mallad 6 Chiara Dalla Man* 7 Giovanni Sparacino* 8 Matthew Johnson 9 Rickey Carter 10 Rita Basu 11 Yogish Kudva 12 Claudio Cobelli* 13 Ananda Basu. 14 15 16 Running Title: Insulin sensitivity during exercise 17

Premature infants of low and extremely low birth weight represent a challenge for neonatal intensive care units and paediatricians. These neonates may be at increased risk of insulin resistance and diabetes perinatally and during childhood. During the first week of postnatal life, infants born prematurely are at risk of abnormalities in glucose homeostasis. Additionally, there are major differe...