A 45-year-old man with neurofibromatosis presented with recurrent seizures due to hypoglycaemia caused by an insulinoma. The attacks were abolished after the successful removal of the insulinoma. This probably represents another example of the association between neurofibromatosis and a tumour consisting of cells with amine-precursor-uptake and decarboxylation.

BACKGROUND Insulinoma is a rare diagnosis in the general population with estimates of 1 in 250,000 people per year. Reports of these pancreatic islet cell tumors are even more unusual in children and adolescents. Chronic hypoglycemia due to an insulinoma often presents with neuroglycopenic symptoms that can easily be overlooked, especially in adolescents where nonspecific complaints are common....

Our institution implemented an inpatient 72-hour fast protocol in 2018 to evaluate for insulinoma patients with hypoglycemia. The ends when spontaneous hypoglycemia is confirmed by a stat venous glucose level ≤45mg/dL, or once 72 hours has elapsed. In its first 2.5 years, 34 completed the at average of 57.6±24.3 hours. could have ended earlier 35% based on elevated beta-hydroxybutyrate (BHB) le...

Abstract Introduction Insulinomas are rare neuroendocrine tumors, with an incidence of 4 cases per one million patient-years. Malignant insulinomas even rarer, a paucity data for specific treatment modalities. Surgery, the mainstay treatment, needs to be determined by disease extent prior resection. Here, we describe patient who presented Federally Qualified Health Center diagnosis hypoglycemia...

In this report, nine patients with insulinoma who were operated on between 19H5 and I <J<J3 at the Shohada Medical Center affiliated to the Shahid Beheshti University of Medical Sciences in Tehran are presented. There were three males and six females (male to female ratio I :2) and the patients' age ranged from 23 to 60 years old (mean age 37.6 years old). Duration of symptoms was from thr...

Malignant insulinoma is very rare in children. Herein, we present a case of a child with malignant insulinoma along with islet cell hyperplasia. She initially presented with features of hyperinsulinemic hypoglycemia at 18 mo of age. Magnetic resonance imaging (MRI) of the abdomen showed a mass at the junction of the head and body of the pancreas. The tumor was enucleated. Five months later symp...

Insulinoma is very rare tumor, patients present with features of profound hypoglycemia, life threatening coma.high degree of suspicion is required for this rare entity. Many patients are erroneously referred to psychiatrists and neurologists. In majority of the cases there is diagnostic delay of years. Some patients even die due to unnoticed severe hypoglycemia. A young male presented to us wit...

The association of diabetes mellitus and insulinoma is unusual. We are reporting the case of a 58 years old patient having diabetes mellitus type 2 for several years. This patient was well balanced with oral anti-diabetic treatment. However, the diagnosis of insulinoma was discussed due to recent episodes of hypoglycemia that persisted even after stopping the treatment. Abdominal CT allowed the...