BACKGROUND Local epidemiological data are always helpful when choosing the best antibiotic regimen, but it is more complex than it seems as it may require the analysis of multiple combinations. The aim of this study was to demonstrate a simplified mathematical calculation to determine the most appropriate antibiotic combination in a scenario where monotherapy is doomed to failure. METHODS The...

Tim Lewis, The Open University Thierry Chanier, Université Blaise Pascal Bonnie Youngs, Carnegie Mellon University This special issue of Language Learning & Technology gathers five studies that deal with a recent development in CALL: multilateral online exchanges for learning language and culture. Multilateral exchanges reflect the changing reality of language learning in a globalized world whe...

Methods Prospective multicenter study of characteristics for repeated blood culture sampling in neonates admitted to three tertiary-referral intensive care units (period 7/201312/2014). Repeated blood culture samples were included when obtained within 14 days after the previous sample. Clinical sepsis is defined as the presence of 2 clinical signs and the duration of antibiotic therapy for ≥5 d...

Congenital nephrotic syndrome (CNS) can be caused by neonatal infections and renal diseases that usually occur in early infancy. The most common CNS is the Finnish type, which is an autosomal recessively inherited disease characterized by intrauterine onset of massive proteinuria. In this study, we presented a preterm neonate confirmed as the first case of CNS in Iran by genetic study, who was ...