There are several reports that adenosine and carbamazepine have
pharmacodynamic interaction. I n this study the antinociceptive interaction o f these
two agents was evaluated in mice by the hot plate test. Agents were injected
intraperitoneally.
0.2 and 0.4 mg/kg doses of R-phenylisopropyladenosine (R-PIA) substantially
showed antinociceptive effects. Carbamazepine had antinociceptive acti...
