objective: helicobacter pylori has a well-established role in the development of gastric cancer. in vitro studies reveal increased proliferation of the gastric mucosa in the presence of h. pylori infection. it has been also shown that production of some cytokines, such as interleukin-1 beta (il-1b) is increased in h. pylori infection. in addition, il-1b increases proliferation of gastric epithe...

Malaria-induced hypoglycemia is recognized as a serious complication of malaria and has one the strongest associations with mortality in children. It been speculated that oxidative stress pro-inflammatory response during parasite infection were involved its pathophysiology. Hence, this study aimed to investigate development malaria-induced Plasmodium berghei ANKA (PbANKA) particular attention i...

INTRODUCTION Several cases of sarcoidosis following treatment with interferon-α have been reported in the literature, but those following interferon-β are very rare. We report the case of a patient with multiple sclerosis who developed pulmonary and cutaneous sarcoidosis following treatment with Betaseron® (interferon-β-1b). CASE PRESENTATION A 33-year-old Caucasian woman with a history of mu...

OBJECTIVE Some previous studies suggest modest to strong effects of 25-hydroxyvitamin D (25(OH)D) on multiple sclerosis (MS) activity. The objective of this study was to explore the mechanistic rationale that may explain potential clinical effects of 25(OH)D. METHODS This study measured serum 25(OH)D levels and global gene expression profiles over a course of up to 2 years in patients startin...

withstand the 20 min rotation, some were not completely immune, perhaps because of residual vestibular function. Some degree of otolith function could still be present since caloric and rotational tests primarily assess horizontal semicircular canal function. It is also known that visual stimuli can provoke symptoms, and since the experiment took place in the light, this may be an alternative e...

The integrin subunit beta 1B, a beta 1 isoform with a unique sequence at the cytoplasmic domain, forms heterodimers with integrin alpha chains and binds fibronectin, but it does not localize to focal adhesion sites (Balzac, F., A. Belkin, V. Koteliansky, Y. Balabanow, F. Altruda, L. Silengo, and G. Tarone. 1993. J. Cell Biol. 121:171-178). Here we analyze the functional properties of human beta...