Chronic intestinal pseudo-obstruction (CIPO) is a syndrome characterized by the presence of recurrent episodes of clinical intestinal obstruction in the absence of obstructive lesions. Although this syndrome is rare, it causes a high morbidity. It is caused by a disturbance of the intestinal motility, that results in a failure of the progression of the intestinal content. Basically, the failure...

The aim of this study was to investigate effects of synchronized intestinal electrical stimulation (SIES) on small intestinal motility in dogs. Seventeen dogs were equipped with a duodenal cannula for the measurement of small bowel motility using manometry; an additional cannula was equipped in six of the dogs with 1.5 m distal to the first one for the measurement of small intestinal transit. T...

Chronic intestinal pseudo-obstruction is a rare intestinal motility disorder. It is characterized by recurrent or persistent findings of intestinal obstruction in the absence of any mechanical obstruction. Various systemic or congenital diseases are held responsible in the etiology; moreover, it is accepted as idiopathic upon failure of detection of a true reason. We present hereby two rare cas...

Intestinal motility disorders are an important problem in the postoperative management of patients with intestinal atresia. Intestinal motility could be initiated by luminal factors that activate intrinsic and extrinsic primary afferent nerves involved in the peristaltic reflex. Endocrine cells act as a key point, because they transfer information regarding the intestinal contents and intralumi...

Pseudo-obstruction is an abnormality of intestinal motility severe enough to produce the clinical features of intestinal obstruction. Normal intestinal motility depends upon the modulation by nerves and hormones of the intrinsic rhythmical contractility of the smooth muscle syncytium. Contraction occurs when hyperpolarising action potentials (spikes or electrical response activity, ERA) coincid...

BACKGROUND & AIMS High-fat diet (HFD) feeding is associated with gastrointestinal motility disorders. We recently reported delayed colonic motility in mice fed a HFD mice for 11 weeks. In this study, we investigated the contributing role of gut microbiota in HFD-induced gut dysmotility. METHODS Male C57BL/6 mice were fed a HFD (60% kcal fat) or a regular/control diet (RD) (18% kcal fat) for 1...

Hepatic encephalopathy (HE) is a common complication in patients with hepatic cirrhosis. Ammonia from intestinal overgrowth with bacteria is the main cause of HE symptoms. Treatment of intestinal bacterial overgrowth with antibiotics that have low gastrointestinal absorption demonstrates the most benefit. However, increasing gastrointestinal motility is another integral part of treatment and cu...

1 Abdullah Göymen1, Yavuz Şimşek2, Şükran Esra Özkaplan1, Halil İbrahim Özdurak1, Yaşam Kemal Akpak3, Altuğ Semiz4, Serkan Oral5 1Department of Obstetrics and Gynaecology, SANKO University, Faculty of Medicine, Gaziantep, 2Department of Obstetrics and Gynaecology, Kırıkkale University, Faculty of Medicine, Kırıkkale, 3Department of Obstetrics and Gynaecology, Dışkapı Yıldırım Beyazıt Training a...

Trained, unanaesthetised dogs with jejunal fistula and adapted to 2 h meal-time showed transient taste-correlated changes in pressure (mm H2O) but not in frequency of intestinal motility. Intestinal pressure was increased on bitter taste both before meal-time (4.7 +/- 0.2 mm) and after it (13.1 +/- 0.9 mm) over respective basal pressure (before meal 3.2 +/- 0.4 mm), after meal 10.6 +/- 1.4 mm),...

OBJECTIVE To investigate intestinal motility changes due to uremia, and the effect of pretreatment with erythropoietin. METHODS This randomized control study was conducted in the Department of Physiology, Faculty of Medicine, Ain Shams University, Cairo, Egypt from September 2010 to July 2011. Forty adult female Wistar albino rats were allocated into 3 groups: control group, gentamicin-treat...