With increasing life expectancy, the demand for preservation of native articular cartilage is increasing to delay joint arthroplasties. In the knee, there are many different strategies to preserve the articular cartilage including but not limited to corrective osteotomies, chondral injury restoration, intraarticular injection of cells or growth factors(PRP). However, One of the most important s...

Mesenchymal stem cells (MSCs) can be obtained from various tissues, and contain common features. However, an increasing number of reports have described variant properties dependent of cell sources. We examined (1) whether MSCs existed in several intraarticular tissues, (2) whether gene expression profiles in intraarticular tissue MSCs closely resembled each other, and (3) whether identified ge...

BACKGROUND Tranexamic acid (TXA) has received extensive attention in management of blood loss in orthopedic surgeries. However, the ideal method of TXA administration is still controversial. This study aims to determine whether intraarticular injection of TXA reduces blood loss after total knee arthroplasty (TKA). METHODS Through a retrospective case-control study consecutive TKA patients rec...

OBJECTIVES Published scoring methods for quantifying synovitis focus on acute inflammatory parameters, and are unsuitable as outcome measures in experimental surgical models of osteoarthritis (OA). The aim of the present study was to define a modified histopathological scoring system for ovine synovium more suited to the chronic pathology induced by ovine meniscectomy, and to apply it to detect...

i f l p j s t hondrolysis of the glenohumeral joint has been reorted to occur after the use of thermal energy, bioaborbable intraarticular implants, intraarticular infusion of upivacaine, and intraarticular injection of gentian vioet dye, as well as after otherwise uncomplicated cases f shoulder arthroscopy during which no such etiologic actors can be identified. Chondrolysis can esult in devas...

Introduction Intraarticular injections are commonly used in children with JIA to induce prompt relief of symptoms of active synovitis, and obtain disease remission as sole therapy or in combination with systemic treatment. In the recent years, the wider use of musculoskeletal ultrasound allowed to detect more precisely the exact site of inflammation and showed to be a safe guide for injection p...

Neglected dislocations of the elbow are not uncommon in developing countries. We report case series of 3 cases of neglected dislocations of elbow. All the three cases were treated by combination of Speeds procedure and intraarticular injection of 25mg of hydrocorticosone acetate in 5 ml of distilled water. Mean time from injury was 5 months and mean follow-up was 10 months. According to Mayo El...

BACKGROUND Postoperative pain after total knee arthroplasty (TKA) can be difficult to manage and may delay recovery. Recent studies have suggested that periarticular infiltration with local anesthetics may improve outcome. METHODS 80 patients undergoing TKA under spinal anesthesia were randomized to receive continuous femoral nerve block (group F) or peri- and intraarticular infiltration and ...