نتایج جستجو برای: intracerebral hematoma

تعداد نتایج: 28068  

Journal: :Neurology India 2009
Santhosh George Thomas Ranjith K Moorthy Vedantam Rajshekhar

We report a 57-year-old man who presented one month after sustaining a traumatic right temporal intracerebral hematoma with history of headache, left hemiparesis and altered sensorium of two days duration. A diagnosis of right temporal resolving hematoma was made on computed tomography scan. However, his sensorium progressively deteriorated and he underwent craniotomy and partial excision of an...

Journal: :Stroke 2014
Christian Ovesen Anders Fogh Christensen Derk W Krieger Sverre Rosenbaum Inger Havsteen Hanne Christensen

BACKGROUND AND PURPOSE Early hematoma expansion (EHE) in patients with intracerebral hematoma is a promising treatment target. To date, the time course of EHE has remained poorly described. We prospectively investigated the time course of EHE. METHODS We included consecutive patients presenting spontaneous intracerebral hematoma within 4.5 hours. On admission, patients underwent noncontrast c...

Journal: :Stroke 2015
Dylan Blacquiere Andrew M Demchuk Mohammed Al-Hazzaa Anirudda Deshpande William Petrcich Richard I Aviv David Rodriguez-Luna Carlos A Molina Yolanda Silva Blas Imanuel Dzialowski Anna Czlonkowska Jean-Martin Boulanger Cheemun Lum Gord Gubitz Vasantha Padma Jayanta Roy Carlos S Kase Rohit Bhatia Michael D Hill Dar Dowlatshahi

BACKGROUND AND PURPOSE Hematoma expansion in intracerebral hemorrhage is associated with higher morbidity and mortality. The computed tomography (CT) angiographic spot sign is highly predictive of expansion, but other morphological features of intracerebral hemorrhage such as fluid levels, density heterogeneity, and margin irregularity may also predict expansion, particularly in centres where C...

Journal: :Stroke 2011
Wei Zhou Sönke Schwarting Sergio Illanes Arthur Liesz Moritz Middelhoff Markus Zorn Martin Bendszus Sabine Heiland Joanne van Ryn Roland Veltkamp

BACKGROUND AND PURPOSE Dabigatran-etexilate (DE) recently has been approved for stroke prevention in atrial fibrillation. However, lack of effective antagonists represents a major concern in the event of intracerebral hemorrhage (ICH). The aims of the present study were to establish a murine model of ICH associated with dabigatran, and to test the efficacy of different hemostatic factors in pre...

Journal: :AJNR. American journal of neuroradiology 2014
R I Aviv T Huynh Y Huang D Ramsay P Van Slyke D Dumont P Asmah R Alkins R Liu K Hynynen

BACKGROUND AND PURPOSE The "spot sign" or contrast extravasation is strongly associated with hematoma formation and growth. An animal model of contrast extravasation is important to test existing and novel therapeutic interventions to inform present and future clinical studies. The purpose of this study was to create an animal model of contrast extravasation in acute intracerebral hemorrhage. ...

Journal: :Stroke 2011
Sergio Illanes Wei Zhou Sönke Schwarting Sabine Heiland Roland Veltkamp

BACKGROUND AND PURPOSE intracerebral hemorrhage associated with oral anticoagulants has a poor prognosis. Current treatment guidelines are based on case series and plausibility only, and a common consensus on effective hemostatic therapy is missing. We compared the effectiveness of diverse hemostatic approaches in a mouse model of warfarin-associated intracerebral hemorrhage. METHODS male C57...

2015
Seung Hwan Kim Jung Soo Kim Hae Yu Kim Sun-il Lee

OBJECTIVE Treatment of spontaneous intracerebral hemorrhage (ICH) remains controversial. However, an extensive hemorrhage with a poor mental status is suitable for surgical evacuation. Our experience with the transsylvian-transinsular (TS-TI) microsurgical approach for deep-seated basal ganglia (BG) ICH was investigated. MATERIAL AND METHODS A retrospective review was conducted on 86 patients...

Journal: :Stroke 2016
Kimihiko Orito Motohiro Morioka

BACKGROUND AND PURPOSE Recent studies of intracerebral hemorrhage treatments have highlighted the need to identify reliable predictors of hematoma expansion. Several studies have suggested that the spot sign on computed tomographic angiography (CTA) is a sensitive radiological predictor of hematoma expansion in the acute phase. However, the spot sign has low sensitivity for hematoma expansion. ...

2013
Tomoya Hirose Naoya Matsumoto Osamu Tasaki Hajime Nakamura Fuyuko Akagaki Takeshi Shimazu

The mechanisms accounting for the development of tissue damage following traumatic brain injury (TBI) have been studied for several decades. A variety of mediators, such as vascular endothelial growth factor (VEGF) and matrix metalloproteinase-9 (MMP-9), which play a crucial role in edema formation after TBI, have been identified. We experienced a case of brain edema that progressed continuousl...

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