Sub arachnoid hemorrhage due to ruptured intracranial aneurysm is a major healthcare concern because of its fatal consequence and also the potential to be fully treated if acted upon on time. It constitutes 85% of nontraumatic SAH cases. 1 The incidence of intracranial aneurysms have been found to be as high as 1% in males and 2% in females in the UK. 2 Although the incidence of patients presen...

Mycotic aneurysms are a rare cause of intracranial aneurysms that develop in the presence of infections such as infective endocarditis. They account for a small percentage of all intracranial aneurysms and carry a high-mortality rate when ruptured. The authors report a case of a 54-year-old man who presented with infective endocarditis of the mitral valve and acute stroke. He subsequently devel...

BACKGROUND Intraoperative rupture of an intracranial aneurysm is a potentially devastating but avoidable and manageable complication of aneurysm surgery. OBJECTIVE To describe a surgical technique that the authors have used successfully to repair a tear at the neck of an intracranial aneurysm, as well as alternative options for managing this intraoperative complication. METHODS The tear on ...

OBJECTIVE To study the features and approaches of endovascular treatment for intracranial aneurysms with a ruptured bleb. METHODS This retrospective study was carried out from June 2007 to June 2009 in Jilin University, Jilin, China. Thirty patients with intracranial aneurysms with ruptured blebs were included. The aneurysms were diagnosed by digital subtraction angiography (DSA), and the end...

BACKGROUND AND PURPOSE Neurofibromatosis type I (NF1) is an autosomal dominant, hereditary, neurocutaneous syndrome purported to be associated with intracranial aneurysms. To study the relationship between NF1 and intracranial aneurysms, we have analyzed all intracranial autopsies of NF1 patients performed at our institution from 1889 to 1999 and analyzed all intracranial aneurysm cases at our ...

BACKGROUND AND PURPOSE The familial occurrence of intracranial aneurysms suggests the presence of a genetically determined underlying arteriopathy. The pattern of inheritance in these families usually is not known. METHODS A family with seven members with intracranial aneurysms is described and, from the literature before 1994, a total of 238 families with 560 affected members (56% female and...

OBJECTIVE SPARC is a key determinant of invasion and metastasis in some tumors, such as gliomas, melanomas and prostate tumors. SPARC can change the composition and structure of the matrix and promote angiogenesis; these effects are closely related to clinical stage and the prognosis of tumors such as meningiomas. However, little is known about the expression of SPARC in intracranial aneurysms....

An intracranial aneurysm in a child or adolescent is a rare, but potentially devastating condition. As little as approximately 1200 cases are reported between 1939 and 2011, with many of the reports presenting diverting results. There is consensus, though, in that pediatric aneurysms represent a pathophysiological entity different from their adult counterparts. In children, there is a male pred...

BACKGROUND AND PURPOSE Distinguishing whether forces resulting from the impingement of central blood flow streams at a curved arterial segment or at the apex of an intracranial bifurcation could be important for the understanding of aneurysm formation. Using finite element models, our purpose was to investigate the hemodynamics related to intracranial saccular aneurysm formation through compute...

OBJECTIVE To report a unique case of wide-necked mycotic cerebral aneurysm treated with a new generation of intracranial stent. CLINICAL PRESENTATION A 10-year-old girl presented with meningitis complicated by an infectious intracavernous large aneurysm revealed by cranial nerve palsy. INTERVENTION The aneurysm was treated by a new-generation, flow-diverting, endoluminal implant (SILK; BALT...