Langerhans cell histiocytosis is a rare disorder which mimics various clinical and radiological presentations including infection or malignancy; symptoms can be mild life threatening.1 It clonal proliferation of myeloid dendritic cells in sites the body, caused by alterations MAPKinase pathway BRAF V600 E. The literature reveals common being skin bones, lymph nodes, brain, lung, liver, spleen.2...

BACKGROUND It is widely recognized that patients have increased anxiety before elective surgery, however, previous research investigating the effect of preassessment clinics (PACs) on anxiety levels has been limited specifically to patient information literature or multimedia use, rather than the consultation process itself. The aim was to investigate the effect attendance at PAC had on patient...

There are more than 200,000 Canadians living with permanent pacemakers or implantable defibrillators, many of whom will require surgery or invasive procedures each year. They face potential hazards when undergoing surgery; however, with appropriate planning and education of operating room personnel, adverse device-related outcomes should be rare. This joint position statement from the Canadian ...

BACKGROUND The touch preparation technique is an accurate and rapid method, and when used as intraoperative consultation examination technique it preserves a good amount of tissue for paraffin embedded sections. This study aimed at examining the accuracy of the touch preparation technique by comparing its diagnosis with that of final pathological diagnosis made by microscopic examinations. ME...

A 4-year-review was carried out on intraoperative frozen section consultations in Sultanah Aminah Hospital, Johor Bahru. Two hundred and fifteen specimens were received from 79 patients in the period between January 1999 and December 2002. An average of 2.72 specimens per patient was received. The overall diagnostic accuracy was high, 97.56%. The diagnoses were deferred in 4.65% of the specimen...

The Eastern Quebec Telepathology Network is aimed at providing uniform diagnostic telepathology services in a huge territory with a low population density. It has been designed to provide intraoperative consultations (frozen sections) in smaller community hospitals and to allow pathologists working alone to rapidly obtain a second opinion. This study provides an interim evaluation of the benefi...

BACKGROUND In women with endometrial hyperplasia, there is a risk for co-existent endometrial cancer when patients are subjected to immediate surgical treatment. AIMS The aim of this study was to investigate the frequency of endometrial cancer and the accuracy of frozen section analysis at the time of hysterectomy among patients with endometrial hyperplasia, to reveal whether or not a preoper...

Intra-operative diagnosis of brain tumours routinely employs frozen sections. The frozen section however has several limitations and induces serious freezing artefacts. We carried out a prospective study on 40 cases of astrocytomas utilizing touch preparation cytology. The smears were quite cellular with crisp cellular details. There was 98.4% sensitivity and 90% specificity. We found touch pre...

This is a retrospective quality assurance study of all frozen sections done at The Aga Khan University Hospital during a six year period (1986 to 1991). There were 1,031 frozen sections out of a cumulative total of 42,985 surgical specimens (2.39%). Nine hundred and severity-six (94.66%) were concordant. In 92 (8.9%) fresh specimens were brought from other hospitals of Karachi, in 37 cases (3.5...