Sodium monofluoroacetate has been shown by Buffa and Peters (1) and Potter and Busch (9) to produce a marked increase in the citric acid con tent of various tissues of animals following injec tions of lethal doses of this compound. Subsequent ly, Buffa et al. showed that the administered fluoroacetate was converted to a fluorinated tn carboxylic acid (s). This compound, a potent corn petitive i...

We examined the ability of human lysozyme (HLZM) to enhance the immunogenicity of a methylcholanthrene-induced murine fibrosarcoma in C57BL/10 mice. Following s.c. injec tion of 10" live tumor cells, 100% of mice developed palpable tumors within 16 ±3 (S.D.) days. Prechallenge immunization with 106 irradiated tumor cells with or without complete Freund's adjuvant resulted in protection from tu...

Intraperitoneal vancomycin is used for empiric treatment of peritoneal dialysis peritonitis. It is dosed intermittently and a high systemic concentration is often achieved. Despite this, there are very few reports of systemic toxicity from intraperitoneal vancomycin. We report the course of a patient who developed a drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome after th...