Fetal growth retardation complicates an average of 10% all pregnancies. Today, ultrasound examination is used in obstetrics for diagnosis. Therefore, early detection this complication the key to adequate treatment and reduction perinatal consequences. A deeper understanding accompanying parameters will allow timely or prevention intrauterine fetal development. The aim research was conduct anten...

OBJECTIVE To determine more precisely the effect of prophylactic low dose aspirin on intrauterine growth retardation and perinatal mortality. DESIGN Meta-analysis of 13 published randomised clinical trials. METHODS We searched 18 medical databases, including MEDLINE since 1964 and EMBASE since 1974, review articles and the references from each retrieved report to identify all studies evalua...

BACKGROUND Approximately 10 percent of infants with intrauterine growth retardation remain small, and the causes of their growth deficits are often unclear. We postulated that mutations in the gene for the insulin-like growth factor I receptor (IGF-IR) might underlie some cases of prenatal and postnatal growth failure. METHODS We screened two groups of children for abnormalities in the IGF-IR...