نتایج جستجو برای: isosorbide dinitrate
تعداد نتایج: 1935 فیلتر نتایج به سال:
اثر ایزوسورباید بر فعالیت تکثیری رده سلولی Wehi-164 و سلولهای منونوکلئر خون محیطی در شرایط In vitro
Background: Isosorbide dinitrate has been broadly used in the treatment of various ischemic heart diseases. Isosorbide is a nitric oxide donor which increases blood flow to tumors through vasodilatation and consequently accelerates the access of chemo-drugs to them. Furthermore, this drug has inhibitory effects on angiogenesis, tumor growth and metastasis in vivo. Moreover, its ant-inflammatory...
In the title compound, C(11)H(15)N(3) (2+)·2NO(3) (-), one of the imidazole N atoms and the N atom of the pyrrolidine ring are protonated. The pyrrolidine ring adopts an envelope conformation, with the C atom carrying the benzoimidazolium substituent as the flap atom. In the crystal structure, cations and anions are linked through N-H⋯O hydrogen bonds, forming chains that run parallel to the c ...
In the centrosymmetric title compound, [Co(C6H12N4O3)2](NO3)2·4H2O, the Co(II) ion, lying on an inversion center, is O,N,O'-chelated by two nitrilo-triacetamide mol-ecules, forming a distorted octa-hedral geometry. In the crystal, extensive O-H⋯O and N-H⋯O hydrogen bonds link the complex cations, nitrate anions and lattice water mol-ecules into a three-dimensional network.
The crystal structure of the title compound, C(10)H(26)N(2) (2+)·2NO(3) (-), exhibits a back-to-back paired double-stacked packing arrangement culminating in an overall double zigzag pattern of the dications. Each pair of double-stacked dications is surrounded by a ring of ten nitrate anions. An intricate three-dimensional N---H...O and N---H...(O,O) hydrogen-bonding network exists in the cryst...
background: nitric oxide (no), a major chemical form of endothelium-derived relaxing factor and an important regulator of vascular tone, is released by endothelial cells. the role of no is not restricted to the vascular system, and it participates in the regulation of renal hemodynamics and renal excretory function. there are increasing evidences indicating that the elevated levels of no play a...
The two benzene rings in the cation of the title compound, C(15)H(18)N(4)O(2) (2+)·2NO(3) (-)·2H(2)O, are almost perpendicular [dihedral angle = 91.6 (2)°]. In the crystal, the components are linked by O-H⋯O, N-H⋯O and C-H⋯O hydrogen bonds.
The cation of the salt, C(18)H(18)N(2)O(2) (2+)·2NO(3) (-), lies about a twofold rotation axis. The pyridinium ring is almost coplanar with the phenyl-ene ring [dihedral angle between rings = 5.69 (9)°]. The crystal structure shows π-π stacking inter-actions [centroid-centroid distance = 3.70 (1) Å] between the pyridinium rings and the phenyl-ene rings, generating a linear chain structure. The ...
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