BACKGROUND Array Comparative Genomic Hybridization (array CGH) is increasingly applied on DNA obtained from formalin-fixed paraffin-embedded (FFPE) tissue, but in a proportion of cases this type of DNA is unsuitable. Due to the high experimental costs of array CGH and unreliable methods for DNA quality testing, better prediction methods are needed. The aim of this study was to accurately determ...

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The possibility of producing chemical fuel (hydrogen) from the solar-thermal energy input using an isothermal cycling strategy is explored. The canonical thermochemical reactive oxide, ceria, is reduced under high temperature and inert sweep gas, and in the second step oxidized by H2O at the same temperature. The process takes advantage of the oxygen chemical potential difference between the in...

We show the multidimensional stability of subsonic phase transitions in a non-isothermal van der Waals fluid. Based on the existence result of planar waves in our previous work [1], a jump condition is posed on non-isothermal phase boundaries which makes the argument possible. Stability of planar waves both in one dimensional and multidimensional spaces are proved.

Here we have devised a new generation of isothermal double-stranded DNA (dsDNA) detection method, termed single primer-triggered isothermal amplification (SAMP). It is very simple only requiring one primer and a few copies of dsDNA in less than an hour are detectable with multiple signal amplification steps.

Isothermal journal bearings have been developed by incorporating heat-pipe cooling. The heat pipe assists in spreading heat rapidly along the bearing circumference, resulting in a very small temperature gradient, low peak temperature, and stable transient thermal behavior. This paper presents a model for the isothermal journal bearings and the results of analyses. The heat pipe in the isotherma...

A novel template-dependent extension based isothermal amplification (TEIA) system with high single-base discrimination capability is developed, where the interference caused by non-specific reaction in isothermal strand displacement amplification (SDA) technique is substantially avoided via using a functionalized template probe, showing potential value in the development and application of SDA ...