The following four possible pathways for itching sensation have been suggested by recent reports. 1) Histaminergic TRPV1-positive pathway: Although histamine-positive nerve fibers cannot strictly be classified as "itch specific" due to their excitation also by pure algogens (making them itch-selective), the existence of a subpopulation of nociceptors responsible for itching is strongly suggeste...

Objectives: (1) To assess the clinical variables adversely affecting quality of life (QoL) in patients with psoriasis and (2) to study correlation between severity extent impact on QoL patient. Materials Methods: After obtaining clearance from Institutional Ethics Committee written informed consent individual subject, consecutive above 18 years attending dermatology outpatient department a tert...

OBJECTIVE The aim of the present study was to investigate Demodex species infestation in patients with ear itching. The relationship between the severity of ear itching and Demodex spp. positivity has not been previously reported in the literature, and we believe that our study will make a significant contribution to the understanding of the etiology of ear itching. METHODS Fifty patients wit...

During trials of aluminium adsorbed diphtheria-tetanus/acellular pertussis vaccines from a single producer, persistent itching nodules at the vaccination site were observed in an unexpectedly high frequency. The afflicted children were followed in a longitudinal observational study, and the presence of aluminium sensitization was investigated in the children with itching nodules and their sympt...

Introduction: Myeloproliferative neoplasms (MPN), including polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF), significantly impact patients’ quality of life (QoL). The symptom burden assessment continuous monitoring using the MPN Symptom Assessment Form Total Score (MPN-10) allows detecting symptomatic changes that may be signs disease progression can used as an in...

background : the imo river basin, nigeria is endemic for onchocerciasis, bancroftian filariasis, loaiasis and mansonellosis. this study was aimed at determining the clinical manifestations of onchocerciasis in this region. methods: a cross-sectional study was carried out in 2006 in umuowaibu i and ndiorji commu­nities in okigwe local government area of imo state, nigeria. consenting individuals...

Increase in usage of digital devices and mandatory e-learning imposed during the Covid 19 pandemic curfew may have given rise to an emerging public health threat eyestrain among undergraduate medical students state. The study aimed assess distribution determine association between screen time spent on different for social media use. A cross sectional, questionnaire based online was done a teach...

BACKGROUND Itching is a leading symptom of chronic hand eczema (CHE) having a great impact on patients. The determinants of itching in CHE are unclear. OBJECTIVE We performed a cross-sectional analysis investigating factors associated with the presence and severity of itch in CHE patients from the CARPE registry. METHODS We present baseline data on itch in relationship with sociodemographic...