نتایج جستجو برای: junction treatment

تعداد نتایج: 1440328  

Journal: :Molecular pharmacology 2008
Jun-ichi Koizumi Takashi Kojima Noriko Ogasawara Ryuta Kamekura Makoto Kurose Mitsuru Go Atsushi Harimaya Masaki Murata Makoto Osanai Hideki Chiba Tetsuo Himi Norimasa Sawada

The epithelium of upper respiratory tissues such as human nasal mucosa forms a continuous barrier via tight junctions, which is thought to be regulated in part through a protein kinase C (PKC) signaling pathway. To investigate the mechanisms of the regulation of PKC-mediated tight junction barrier function of human nasal epithelium in detail, primary human nasal epithelial cells were treated wi...

Journal: :Journal of andrology 2000
J P Wiebe A Kowalik R L Gallardi O Egeler B H Clubb

Intratesticular injections of glycerol have been shown to result in a marked and prolonged reduction of spermatogenesis, accompanied by increased permeability of the blood-testis barrier. Because the permeability of the blood-testis barrier is regulated by Sertoli cell tight junctions, and tight junction organization is regulated by the cytoskeleton, we undertook to examine the effects of glyce...

2017
Cong Zhang Junkai Yan Yongtao Xiao Yujie Shen Jiazheng Wang Wensong Ge Yingwei Chen

Tight junction dysfunction plays a vital role in some chronic inflammatory diseases. Pro-inflammatory cytokines, especially tumor necrosis factor alpha (TNF-α), act as important factors in intestinal epithelial tight junction dysfunction during inflammatory conditions. Autophagy has also been shown to be crucial in tight junction function and claudin-2 expression, but whether autophagy has an e...

2016
Panayiotis D. Megaloikonomos Vasilios Igoumenou Thekla Antoniadou Andreas F. Mavrogenis Konstantinos Soultanis

Craniovertebral junction tuberculosis is rare, accounting for 0.3 to 1% of all tuberculous spondylitis cases. MR imaging is the modality of choice to detect bone involvement, abscess formation and subligamentous spreading of the pus, to differentiate from other lesions affecting the craniovertebral junction, and to determine the efficacy of treatment. Given the fact that surgical treatment of p...

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