This manuscript describes our participation in the International Skin Imaging Collaboration’s 2017 Skin Lesion Analysis Towards Melanoma Detection competition. We participated in Part 3: Lesion Classification. The two stated goals of this binary image classification challenge were to distinguish between (a) melanoma and (b) nevus and seborrheic keratosis, followed by distinguishing between (a) ...

Current trends in our setting indicate that the prevalence of actinic keratosis and similar diseases will increase in coming years and impose a greater burden on health care resources. A long list of clinical features must be taken into account when approaching the treatment of actinic keratosis. Until recently, therapeutic approaches focused solely on ablative procedures and the treatment of i...

localization of keratins and involucdn in solar keratosis and Bowen's disease. Am J Dermatopathol 1995; 17: 151-157. 4. Mai K.T. Alhalouly T. Landry D, Stinson WA. Perkins DG, Yazdi HM. Pagetoid variant of actinic keratosis with or with -out squamous cell carcinoma of sun-exposed skin: a lesion simulating extramammary Paget's disease. Histopathology 2002; 41:331-336. 5. Ansai S. Mihara I. Sebac...

Keratosis follicularis (Darier's disease) is a rare (1 in 30,000-100,000) genetic autosomal-dominant predominantly dermatological disorder characterized by hyperkeratosis and acantholysis due to a defective calcium transport in the cells. Ocular findings, if present, are very rare in this condition. Here, we are reporting a case of keratosis follicularis (Darier's disease) with ocular manifesta...

To the Editor, Merkel cell carcinoma (MCC) commonly presents as a malignancy confined to the dermis. Fewer than 10% of cases show varying degrees of epidermal involvement.1 Only a small number of cases of entirely intraepidermal ‘in situ’ MCC (MCCIS) have been reported.2– 8 All but one7 of these cases were encountered as an incidental histopathological finding in the presence of an otherwise co...

The increasing incidence of melanoma prompts a need for efficient management of this patient group. In this study, we use the number needed to excise (NNE), as a measurement of the efficiency of diagnosing melanoma. From January 2009 to December 2012, postoperative records from all patients were prospectively registered. All excised tumours with the histopathological diagnosis of naevus, melano...

Psoriasiform Keratosis is a rare clinic entity. The etiopathogenesis remains unknown and the disease is characterized by a solitary, scaly or keratotic papule, or plaque mainly located on the extremities. Histopathological features closely resemble those of psoriasis. We report the case of a 70-year-old woman presenting a solitary and asymptomatic keratotic plaque, located on the back of the le...

OBJECTIVE The aim of this study was to investigate p53 and COX-2 expressions in basal cell carcinoma, squamous cell carcinoma and actinic keratoses, and to determine a possible relationship. MATERIAL AND METHOD 50 basal cell carcinoma, 45 squamous cell carcinoma and 45 actinic keratosis cases were evaluated. The type of tumor in basal cell carcinoma and tumor differentiation in squamous cell ...