Nutritional ketosis may enhance cerebral energy metabolism and has received increased interest as a way to improve or preserve performance and resilience. Most studies to date have focused on metabolic or neurological disorders while anecdotal evidence suggests that ketosis may enhance performance in the absence of underlying dysfunction. Moreover, decreased availability of glucose in the brain...

The cerebral metabolic activity of glucose and ketones was compared in ketotic rats with insulin-dependent diabetes mellitus (IDDM) and in normal controls. In the IDDM rats, ketosis had been present < 12 hours and the diabetes was of recent onset. After sufficient infusion of labeled [1-13C]glucose to achieve steady-state levels, the ratio of the fractional enrichment of the metabolites [4-13C]...

A 2-year-old boy was admitted with diagnosis of diabetes debut, with blood glucose of 500 mg% on admission, without ketosis or metabolic acidosis. He also presented bilious vomiting and brownish bloody stools. He was operated with a presumptive diagnosis of acute intestinal obstruction. The final diagnosis was volvulus, secondary to congenital malrotation. After surgery, he normalized blood sug...

We present the clinical case of a patient who was admitted with an onset of diabetes mellitus (DM) with associated ketosis and whose clinical, hormonal, and radiological evolution revealed the presence of primary hyperparathyroidism, pancreatic neuroendocrine tumor, and GH-producing pituitary macroadenoma in the context of multiple endocrine neoplasia type 1 (MEN1). DM is relatively common in c...

Mammary uptakes of glucose and long-chain fatty acids are proposed to be the major metabolic determinants of milk volume production and mammary efficiency, respectively. Moreover, the ratio of glucogenic to lipogenic nutrients in the diet is proposed to be the major determinant of spontaneous ketosis. Experimental evidence and clinical observations are adduced in support of these three interrel...

Ketosis is an important metabolic disease of high milk-producing cows. There are significant changes in many metabolite and hormonal concentrations in metabolic diseases. This study was carried out to assess the concentrations calcium (Ca), selenium (Se), total antioxidant (TAOC), insulin, free triiodothyronine (fT3) and free thyroxine (fT4) in cows with subclinical and clinical ketosis. This s...

the prevalence of sub-clinical ketosis and its predisposing factors were assessed in three dairy farms with different sizes (large, medium, small) and different facilities, and with constant management routines. eighty-one cows within the first two months of lactation were sampled for blood. the concentrations of beta-hydroxybutyrate and glucose were determined in blood serum. rations were anal...