نتایج جستجو برای: keywords microrna
تعداد نتایج: 2014780 فیلتر نتایج به سال:
in the retinoblastoma research, it is of great interest to identify molecular markers associated with the genetics of tumorigenesis. micrornas (mirnas) are small non-coding rna molecules that play a regulatory role in many crucial cellular pathways such as differentiation, cell cycle progression, and apoptosis. a body of evidences showed dysregulation of mirnas in tumor biology and many disease...
objective: the aim of the present study was the production of recombinant lentviruses that express mir-16. after transduction, altered expression levels of mirna and its target protein were analyzed. methods: a dna fragment that contained the mir-16 precursor was cloned in a lentiviral plasmid. lentiviral vector particles were produced by transient calcium phosphate co-transfection of 293t cell...
سرطان، نتیجه ی عملکرد نادرست ژنوم و تغییر الگوی بیان ژنی در سلول هاست. در بیشتر سرطان های سینه، یکی از ژن هایی که افزایش بیان نشان می دهد، ژن tpd52 (tumor protein d52) است. این افزایش بیان، باعث افزایش رشد مستقل از سطح سلول ها می شود. بنابراین، شاید با کاهش بیان این ژن، بتوان به درمان این سرطان ها کمک کرد. یکی از روش های کاهش بیان ژن ها، مهار پس از رونویسی آن ها و یک روش نوین این کار، استفاده ا...
This article pursues two tasks. The first is to clarify the value and productivity of Williams’s Keywords: a vocabulary culture society (first edition 1976, second expanded 1983a) for project Cultural Studies. clarification helped, I argue, by reading it alongside Vološinov’s Marxism philosophy language (published in Russian 1929, translated into English 1973). related task speculative developm...
We study the development of conjunctive keyword searchable scheme which enables one to search encrypted documents by using more than one keyword. The notion of conjunctive keyword searching was presented by Golle et al. in 2004. However, their security model was constructed in a symmetric-key setting which is not applicable for the overall applications in the reality. So Park et al. extended Go...
In this paper we present several proofs on the extension of M. Riesz fractional integration and di¤erentiation to the contexts of spaces of homogeneous type and measure metric spaces with non-doubling measures. 1. Introduction, some de nitions, and a basic lemma Professor M. Ash asked me to write a survey article on some of the results that Stephen Vági and I obtained in the nineties on fractio...
To investigate the mechanism of lidocaine in inhibiting proliferation, migration and invasion breast cancer cells. Human cell line Michigan Cancer Foundation-7 cells were treated with lidocaine. Cell proliferation was detected by 2,5-diphenyl-2H-tetrazolium bromide, Transwell, microRNA-495-3p expression quantitative reverse transcription polymerase chain reaction fibroblast growth factor 9, cyc...
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