conclusions our results suggested that cb-nk cells progenitors could proliferate and differentiate on feeder layer of amnion membrane mscs in combination with specific cytokines to produce nk cells for immunotherapy. results combination of cytokines and msc layer yielded significant fold expansion in comparison with cytokines without feeder conditions (day 7: 5.2 ± 1.12 and 2 ± 0.78, respective...

allergic rhinitis  (ar) is  an  inflammatory  disorder  of  the  nasal  mucosa  with  high morbidity and prevalence. natural killer (nk) cells might have a role in ar. we aimed to evaluate the changes of the markers and receptors on nk cells in ar patients compared to the non-atopic controls. flow  cytometric  analysis was  used  with  double  staining  of  the  peripheral  blood mononuclear ce...

it has been demonstrated that natural killer (nk) cells play a role in regulation of autoimmunity. they play a protective role in several rodent disease models. in this study we aimed to compare the immunophenotypic features of nk cells in ankylosing spondylitis (as) with normal subjects with regard to cd56 and cd16 molecules. this study was carried out on 30 as patients and 33 normal volunteer...

results the ovarian hormones level showed a significant difference between the experimental and control groups (p < 0.05). furthermore, the unk cell population showed a significant difference between the two groups (p < 0.05). conclusions increased ovarian hormones due to low-dose aspirin administration resulted in decline in the unk cells number, which may be effective in successful pregnancy....

One of the key objectives of evolving communication technologies is to maximize the utilization of the available spectrum by increasing the number of simultaneous users while reducing interferences among users. In cognitive radio networks, this problem is referred to as the spectrum allocation problem, and is shown to be NP-Hard. This chapter studies the use of evolutionary algorithms to solve ...

Background:  Natural Killer cells express killer inhibitory receptors specific for HLA-class I molecules.  These receptors could induce signals that determine NK cells ability to mediate cytotoxicity.  Purified soluble form of HLA class I molecules (sHLA) could bind to NK cell receptors and down-regulate the NK killer function. Objective:  To evaluate the influence of sHLA and two monoclonal an...