MOTIVATION Realistic simulation of the kinetic properties of metabolic pathways requires rate equations to be expressed in reversible form, because substrate and product elasticities are drastically different in reversible and irreversible reactions. This presents no special problem for reactions that follow reversible Michaelis-Menten kinetics, but for enzymes showing cooperative kinetics the ...

Cluster distribution kinetics is adopted to explore the kinetics of polymer crystallization. Population balance equations based on crystal size distribution and concentration of amorphous polymer segments are solved numerically and the related dynamic moment equations are also solved. The model accounts for heterogeneous or homogeneous nucleation and crystal growth. Homogeneous nucleation rates...

We study universality in the kinetics of spinodal phase separation in unstable thin liquid films, via simulations of the thin film equation. It is shown that, in addition to morphology and free energy, the number density of local maxima in the film profile can also be used to identify the early, late, and intermediate stages of spinodal phase separation. A universal curve between the number den...

Adsorption kinetics for removal of arsenic was carried out by red mud and its mixtures with haematite, china clay and fly ash besides china clay-fly ash at: adsorbate conc., 5.0 mg1; particle size of adsorbent, <53 μm; agitation rate, 220 rpm; pH, 8.0; and temp., 30, 40 & 50°C. Data fit into Lagergren equation and adsorption follows first order reaction kinetics. As(III) removal by adsorbents i...

the kinetics of mn(vii) oxidation of lysine in moderately sulfuric acid solutions was studiedspectrophotometrically in the presence and absence of mn(ii) as catalyst. the reaction was arrangedto be under pseudo first-order condition with respect to mn(vii). the results showed that the pseudofirst-order rate constant increases with increasing [h2so4], [(mn)ii], and [lysine]. the dependence ofthe...

Stochastic trajectories in single molecule kinetics coupled to several Gaussian Markovian coordinates are analyzed using a generating function obtained by solving the multidimensional Smoluchowski equation. Multitime correlation functions are computed and used to identify direct signatures of non-Poissonian kinetics resulting from coupling to slow coordinates. Effects of various degrees of corr...

We discuss the interbasin kinetics approximation for random walk on a complex landscape. We show that for a generic landscape the corresponding model of interbasin kinetics is equivalent to an ultrametric diffusion, generated by an ultrametric pseudodifferential operator on the ultrametric space related to the tree of basins. The simplest example of ultrametric diffusion of this kind is describ...

The investigation was concerned with design and characterization of oral controlled release matrix tablets of Zidovudine (AZT) in order to improve efficacy and better patient compliance. Tablets were prepared by direct compression method using various proportion of hydrophilic polymer viz; Eudragit RS100 and RL100 along or in combination with hydrophobic polymer ethyl cellulose. In vitro releas...

The principal motivation for the present work was the study of the kinetics of anaerobic metabolism. A new mathematical model of the bioenergetics of sprinting, incorporating a three-equation representation of anaerobic metabolism, is developed. Results computed using the model are compared with measured data from the mens' finals of the 100m event at the 1987 World Championships. The computed ...

The isothermal and nonisothermal crystallization kinetics of monoglyceride (MAG) organogels were studied by pulsed nuclear magnetic resonance (pNMR) and differential scanning calorimetry (DSC), respectively. The Avrami equation was used to describe the isothermal crystallization kinetics and experimental data fitted the equation fairly well. Results showed that the crystal growth of MAG organog...