Progressive macular hypomelanosis is an acquired skin pigmentation disorder that was initially thought to be related to racial characteristics, but is currently more often associated with the presence of Propionibacterium acnes. A 23-year-old woman was seen for the progressive appearance over a 5-year period of asymptomatic whitish lesions on the trunk (Figures 1A and 2). The lesions were poorl...

A case of a 75 year old woman with drug-induced bullous pemphigoid is reported. Lesions also involved the site of a burn scar. Systemic steroid therapy proved to be effective on all lesions except for the ones located on the burn scar. In this patient the scarred area acted as a ‘vulnerable’ site, not only facilitating the localization of bullae on the scar (Koebner phenomenon), but also render...

Despite considerable overlap, the confusion hovering over the four common sparing signs can be cleared as follows: Reverse Koebner relates to sparing by physical trauma; isotopic non-response/reverse isotopic response relates to sparing over an already healed dermatosis; Renbok Phenomenon relates to sparing among two concomitant active diseases often with autoimmune etiology; anatopic phenomeno...