A study of label-free silicon nitride asymmetric double-microring resonators is presented. The use highly accurate 3D vector modal techniques permits an extensive exploration the parameter space defining architecture proposed device in search for optimal geometries and reaching configurations not addressed previous studies that had been limited to symmetrical configurations. Asymmetry, on other...

Label-free LC-MS methods are attractive for high-throughput quantitative proteomics, as the sample processing is straightforward and can be scaled to a large number of samples. Label-free methods therefore facilitate biomarker discovery in studies involving dozens of clinical samples. However, despite the increased popularity of label-free workflows, there is a hesitance in the research communi...