in this paper we define a new labeling called skolem odd difference mean labeling and investigate skolem odd difference meanness of some standard graphs. let g = (v,e) be a graph with p vertices and q edges. g is said be skolem odd difference mean if there exists a function f : v (g) → {0, 1, 2, 3, . . . , p + 3q − 3} satisfying f is 1−1 and the induced map f : e(g) → {1, 3, 5, . . . , 2q−1} d...

The postnatal development of rat sublingual glands was analyzed by morphometric and radioautographic studies. The absolute number of each cell type was evaluated by the Aherne II morphometric method for cell counting and labeling indices of these cell types were determined in radioautographs from animals injected with 3H-thymidine. The quantitative cell population kinetic studies were accompani...

An in vitro study of proliferative activity as shown by immunohistochemical detection of the uptake of bromodeoxyuridine was run on rectal biopsies from 400 patients with nonfamilial large bowel neoplasia: 200 adenoma; 150 adenocarcinoma; 50 adenoma plus adenocarcinoma. The controls were 400 subjects with negative personal and family histories of colorectal neoplasia. The number and height dist...

BACKGROUND/PURPOSE Most patients with hepatocellular carcinoma in Japan also have liver cirrhosis. Therefore, reliable information about liver function is essential before undertaking liver resection. Occasionally preoperative estimates and intraoperative findings are disparate. This study used rats with liver fibrosis and a new tactile sensor to determine whether quantification of liver hardne...

Uterine smooth muscle tumor is very rare in laboratory rats and, there has been no report in the wild rodents. Among a total of 400 wild rats captured in Gyeonggi, Gangwon, and Chungbuk provinces of Korea in 2007, 2010, and 2011, we found a uterine spindle cell tumor, diagnosed as smooth muscle cell origin based on differential features of histology and immunohistochemistry. Its incidence was v...

The aim of our study was to investigate the correlation of the proliferative activity of pituitary neoplasms with clinical characteristics and recurrences. Tumor specimens were obtained from 44 consecutive patients with pituitary macroadenomas who underwent surgery between July 1998 and August 2003. Specimens were immediately fixed in 10% buffered formalin and then embedded in paraffin. The Ki-...

Introduction: Diagnosis of neurofibroma usually is based on the specific morphology and arrangement of mesenchymal cells in routine Hematoxylin and Eosin (H&E) sections, and detection of mast cells supports the diagnosis. Sometimes definite diagnosis from other mesenchymal lesions may be difficult. The aim of the present study was to compare S100 expression and mast cells count (as Gold Standar...

The aim of this study is to describe rare variants of adrenocortical carcinoma (ACC) and to compare the prognosis with that of conventional ACC. We retrospectively reviewed 8 cases of myxoid variant, 1 sarcomatoid variant, and 14 cases of conventional ACC, who underwent surgical resection at the Asan Medical Center between 1996 and 2014. An analysis of the clinicopathological characteristics, i...

In many vertebrate species, polyploid and binucleate cells are found in the adult hepatic parenchyma. The number of polyploid and binucleate hepatic cells increases with age. In this paper, the proliferative capacity of polyploid and binucleate cells were studied, in order to analyse a progressive reduction with age in the regenerative capacity of tissues. Three groups of rats, 4-week, 6-week a...

Combined chemotherapy and prophylactic cranial irradiation has improved the prognosis of children with acute leukemia. However cranial irradiation carries a latent risk of the induction of secondary intracranial tumors. We encountered a patient who developed multiple intracranial radiation-induced meningiomas (RIMs) 25 years after prophylactic cranial irradiation for the treatment of acute leuk...