OBJECTIVE To assess the introduction of Practical Obstetric Multi-professional Training (PROMPT) into maternity units and evaluate effects on organisational culture and perinatal outcomes. DESIGN A retrospective cohort study. SETTING Maternity units in eight public hospitals in metropolitan and regional Victoria, Australia. POPULATION Staff in eight maternity units and a total of 43,408 b...

Serum LDH activities assayed spectrophotometrically by the “forward” (lactate + DPN to pyruvate + DPNH + H) method have linear reaction rates, activity proportional to the amount of serumadded,anda reproducibilityof 1.3%. The reagent mixtore can be stored frozen for 6 monthsand in the lyophilized state indefinitely. Poor separationof normal from abnormal serum LDH activities results from the no...

Purpose Diagnosing Leigh syndrome (LS), a representative mitochondrial disease, remains challenging. Mitochondrial DNA (mtDNA)-associated LS, which is maternally inherited, has relatively well-known genetic variants. We evaluated the usefulness of brain magnetic resonance spectroscopy (MRS) for initial diagnosis mtDNA-associated LS using data from patients. Methods The study involved patients w...

A fractionation of sulphur isotopes was found in all hetabolic processes investigated except those in which elemental sulphur was the starting substrate for growth of Thiobacillus concretivorus and Chromatiurn sp. and for reduction by Saccharomyces cerevisiae. Except for polythionates formed during sulphide oxidation by T. concretivorus or Chromatiurn sp., the products of metabolism were enrich...

Bragg, P. D. (University of British Columbia, Vancouver, B.C., Canada), and W. J. Polglase. Enzymatic activities of streptomycin-dependent Escherichia coli in relation to valine formation. J. Bacteriol. 88:1399-1402. 1964.-The activities of several enzymes were compared in antibiotic-depleted and antibiotic-supplemented streptomycin-dependent Escherichia coli. Depleted cells were somewhat lower...

INTRODUCTION Chronic venous insufficiency (HVI) is manifested by the progressive signs of venous stasis. This disorder is treated by: compressive bandaging, medicaments, sclerotherapy, surgery, etc. AIM Prospective study of the effects of semisynthetic diosmin (clinical signs, quality of life, local biochemical parameters) on patients with HVI to whom no other method of treatment has previous...

BACKGROUND We tested the hypothesis that sodium nitroprusside (SNP) might improve the impairment of hepatosplanchnic microcirculatory blood flow (MBF) in septic shock. METHODS Fourteen pigs were anaesthetized and their lungs mechanically ventilated. Sepsis was induced with i.v. infusion of live Pseudomonas aeruginosa [1x10(8) colony forming units (CFU) ml(-1) kg(-1)] for 1 h. Sixty minutes la...

The metabolic characteristics of five muscle groups in the spiny lobster Jasus edwardsii were examined in order to compare their anaerobic and oxidative capacities. Enzyme activities of phosphorylase, phosphofructokinase, pyruvate kinase, and lactate dehydrogenase were highest in abdominal muscles supporting anaerobic burst activity. Hexokinase, citrate synthase, and HOAD activities in the leg ...

A 50-year-oldmanwith alcoholic liver cirrhosis was admitted to our emergency department with massive hematochezia and hypovolemic shock. On admission, laboratory data included hemoglobin 3.1g/dL, hematocrit 9.9%, platelet count 81×109/L, lactates 13.9mmol/L, and international normalized ratio 1.29. Resuscitation was initiated with intravenous fluids and transfusion of 4 units of packed red bloo...

BACKGROUND Patients with sepsis admitted to the intensive care unit often present with acid-base disorders. As the traditional interpretation might be clinically misleading, an alternative approach described by Stewart may allow one to quantify the individual components of acid-base abnormalities and provide an insight into their pathogenesis. The aim of our study was to compare the traditional...