Serotonin regulates numerous processes in the mammary gland. Our objective was to discover novel genes, pathways and functions which serotonin modulates during lactation. The rate limiting enzyme in the synthesis of non-neuronal serotonin is tryptophan-hydroxylase (TPH1). Therefore, we used TPH1 deficient dams (KO; serotonin deficient, n = 4) and compared them to wild-type (WT; n = 4) and rescu...

I . A combination of balance and isotope techniques has been used to study calcium metabolism in ten sheep at different stages of pregnancy, and the results have been combined with earlier results obtained during lactation to show the variations in Ca metabolism which occur during the whole reproductive cycle. 2. Transfer of Ca to the foetuses during pregnancy and to the milk after parturition ...

Abstract In cows embryo transfer occurs on the 7 th day of oestrous cycle. Embryo survival and successful pregnancy depend many factors, including early interaction between endometrium. Therefore, aim our research was to describe histo-morphological characteristics endometrium in donor recipient obtaining day, respectively (7 oestrus cycle). addition, progesterone oestradiol levels, ipsilateral...

The potential for a considerable formation of ornithine exists in lactating mammary gland because of its arginase content. Late in lactation arginase reaches an activity in the gland higher than that present in any rat tissue except liver. Occurrence of the urea cycle can be excluded since two enzymes for the further reaction of ornithine in the cycle, carbamoyl phosphate synthetase I and ornit...

The molecular events underlying the lactation curve of dairy animals have long been a biological conundrum for mammary biologists, and cause considerable loss income farmers. To better understand regulatory mechanisms developmental processes gland during cycle, whole-genome transcriptome profiles bovine tissues at five different stages were investigated using RNA-Seq technique. differentially e...

Much evidence suggests that prolactin (PRL) has an immunoregulatory function. Part of this evidence is that the receptors for PRL are present on lymphocytes. Probably the effects of PRL on cells of the immune system depend on the level and specific forms of PRL-R present on the target cells. Therefore, PRL-R expression at both protein and mRNA levels was examined during oestrous cycle, pregnanc...

An experiment was conducted to determine fatty acid (FA) pro?les in Chinese Maiwa yak milk across the lactation cycle. Sixty-one healthy, similar weight, 4-7 years old, 3-6 parity yaks with unrelated background were selected randomly from Hongyuan County, Sichuan province, southwest of China (with altitude over 3500 m). The graze on natural pasture all year around without irrigation, fertilizer...

During lactation, the levels of neuropeptide Y (NPY), which plays an important role in mediating food intake, are significantly elevated in a number of hypothalamic areas, including the arcuate nucleus (ARH). To identify additional hypothalamic systems that might be important in mediating the increase in food intake and alterations in energy homeostasis during lactation, the present studies exa...