We generated a neonatal pig model with human infant gut microbiota (HGM) to study the effect of a probiotic on the composition of the transplanted microbiota following rotavirus vaccination and challenge. All the HGM-transplanted pigs received two doses of an oral attenuated rotavirus vaccine. The gut microbiota of vaccinated pigs were investigated for effects of Lactobacillus rhamnosus GG (LGG...

In evaluating the therapeutic efficacy of gammaglobulin preparations in patients with agammaglobulinemia, opsonic activity of patients' sera in terms of oxygen consumption capacity of normal leukocytes is advocated as a useful index. Although the serum lgG level is a commonly used indicator, its determination alone was found out not always to reflect antibody levels in such sera. The method des...

The gut microflora is an important constituent in the intestinal mucosal barrier and has been introduced as the concept of probiotic therapy that beneficially affects the host by improving its intestinal microbial balance. Therefore, the main objective of the study was to explore the protective potential of various lactobacilli strains for murine giardiasis. By experimentation, it was found tha...

Use of a visible laser in an Aminco “Rotochem” centrifugal analyzer enables light-scattering measurements to be made with this instrument. The modification is technically simple, inexpensive, and requires no fundamental changes in basic instrument design. The laser-modified analyzer has been applied to the measurement of lgG in serum. A two-point kinetic analysis is used to quantitate lgG from ...

BACKGROUND Probiotic supplementation in early life may be effective for preventing eczema. Previous studies have suggested that prenatal administration may be particularly important for beneficial effects. OBJECTIVE We examined whether prenatal treatment with the probiotic Lactobacillus rhamnosus GG (LGG) can influence the risk of eczema during infancy. METHODS We recruited 250 pregnant wom...

Objective: Study the influence of pre-competition intensive training on B lymphocyte immunity of excellent track and field athletes. Method: Select 10 excellent track and field athletes of the school to receive pre-competition intensive training and observe the influence of long-time training and competition on B lymphocyte immunity of these athletes. Result: In this study, the concentration of...

In a previous communication (Barber et al. [1 ] ) it has been shown that there exists in human serum a cobalt-activatable enzyme which splits 1leucylglycylglycine (LGG). The rate of hydrolysis in normal adult individuals is between 5.5 and 8.5% per hour (in the previous communication the rate of hydrolysis of LGG by serum of normal adult controls was stated to be 6.1 to 7.8%o per hour. This val...

The strong ropy character of the Scandinavian fermented milk viili is conferred by the exopolysaccharides (EPS) produced by lactococcal strains. These biopolymers can be responsible for some health benefits. We have assessed the influence of the EPS fraction isolated from commercial viili on the adhesion of some probiotics and pathogens to human intestinal mucus. Concentrations of viili EPS gre...

lsologous antigenic determinants of y-globulin revealed by proteolytic digestion of the globulin molecules were discovered by Osterland, Harboe, and Kunkel (1963) in human lgG and by Mandy, Fudenberg, and Lewis (1965) in rabbit y G. These determinants are detected by autologous and isologous antibodies found in most human sera and in all rabbit sera, respectively. These antibodies were named pe...