Immunohistochemistry was used to identify, enumerate, and describe the tissue distribution of Langerhans type (CD1a and CD207), myeloid (CD1c and CD141), and plasmacytoid (CD303 and CD304) dendritic cell subsets in oral mucosa of allergic and non-allergic individuals. Allergic individuals have more CD141+ myeloid cells in epithelium and more CD1a+ Langerhans cells in the lamina propria compared...

We present the case of an 18-year-old woman admitted to our hospital with persistent epigastric pain lasting two months and a weight loss of approximately 5 kg during the same period. She had no history of alcohol, tobacco, steroid, anticoagulant, or nonsteroidal anti-inflammatory drug use. Investigations were initiated with informed consent. Laboratory test results were: hemoglobin, 13 g/dL; w...

BACKGROUND The presence of tactile corpuscle-like structures in Schwannomas, Neurofibromas and Neuroid Intradermal Melanocytic Nevi is well-documented. We report a case describing the presence of such structures in the lamina propria of grossly normal gastric mucosa. CASE PRESENTATION A 30 year-old male underwent esophagogastrectomy for carcinoma. Examination of hematoxylin and eosin stained ...

Figure 2. High-power micrograph (original magnification, 600) of the appendix specimen shows mucosal cells with characteristic cytomegalovirus inclusions (arrow); note the “owl-eye” intranuclear inclusions and granular cytoplasmic inclusions. Figure 1. Low-power micrograph (original magnification, 40) of a longitudinal section of the appendix demonstrates mucosa ulcerated with a lymphohistiocyt...

a histological and histochemical study of the stomach (proventriculus and gizzard) of the passer domesticus was carried out, under light microscopy.in the present study, we prepared 12 adult passer domesticus (both sex) captured in the country side of mashhad, iran. after euthanasia with ether inhalation, the digestive tract was exposed and fragments of the stomach (proventriculus and gizzard) ...

OBJECTIVES To study the effect of short-chain fatty-acids on atrophy and inflammation of excluded colonic segments before and after the development of diversion colitis. INTRODUCTION Diversion colitis is a chronic inflammatory process affecting the dysfunctional colon, possibly evolving with mucous and blood discharge. The most favored hypotheses to explain its development is short-chain fatt...

We used a whole-genome microarray screening system (Affymetrix human GeneChips covering 47,000 different transcripts) to examine the gene expression in duodenal mucosa during acute cholera. Biopsies were taken from the duodenal mucosa of seven cholera patients 2 and 30 days after the onset of diarrhea, and the gene expression patterns in the acute- and convalescent-phase samples were compared p...

An 1-year-old male Basset Hound dog was evaluated for chronic intermittent vomiting, hematemesis, and melena which had been ongoing for several months. The histopathologic examination revealed that all layers of the small intestine were thicker than normal. The lamina propria of the mucosa, including the villi, exhibited a prominent cellular infiltrate which consisted of numerous eosinophils an...

OBJECTIVE Intestinal gamma/delta- intraepithelial lymphocytes (IEL) have increased in children with juvenile idiopathic arthritis (JIA). To further characterise intestinal immune activation in these children, we have quantitated cytotoxic lymphocytes in intestinal mucosa. METHODS We studied 23 children with JIA suffering from gastrointestinal symptoms with gastroduodenoscopy and colonoscopy. ...

In 3 cases of acrodermatitis enteropathica duodenal biopsy performed at the outset of treatment showed a similar abnormality of the intestinal mucosa. Further biopsies taken during treatment showed progressive improvement of the intestinal mucosa with subsequent complete restoration of the normal cellular and villous pattern. The initial treatment was with expressed human breast milk and oral d...