Diabetes is characterized by hyperglycemia that can result from the loss of pancreatic insulin secreting β-cells in the islets of Langerhans. We analyzed ex vivo the entire gastric and duodenal lobes of a murine pancreas using extended-focus Optical Coherence Microscopy (xfOCM). To identify and quantify the islets of Langerhans observed in xfOCM tomograms we implemented an active contour algori...

Subtle structural differences can be observed in the islets of Langerhans region of microscopic image of pancreas cell of the rats having normal glucose tolerance and the rats having pre-diabetic (glucose intolerant) situations. This paper proposes a way to automatically segment the islets of Langerhans region from the histological image of rat's pancreas cell and on the basis of some morpholog...

Nuclear microscopy is a suite of techniques based on a focused beam of MeV protons. These techniques have the unique ability to image density and structural variations in relatively thick tissue sections, map trace elements at the cellular level to the microgram per gram (dry weight) level, and extract quantitative information on these elements. The trace elemental studies can be carried out on...

The alcoholic extract of Swertia chirayita was tested for its biochemical and pathomorphological effects in streptozotocin induced diabetes rats. Streptozotocin produced effectively all the animals at 45 mg/kg b.w. intraperitonially. diabetic showed significant increase serum levels glucose, cholesterol, triglycerides, ALT AST a reduction insulin levels. treated rats dose 500 b.w with improveme...

Pancreatic infiltration with eosinophils is an uncommon finding with numerous etiologies. While two rare cases of eosinophilic pancreatitis in infants born to Type I diabetic mothers have been reported once in the English literature and once in the French literature, we present the additional finding of anencephaly in a 34 week old fetus. Although the pancreas was grossly unremarkable, histolog...