A survey is given of upper respiratory tract tumors in Cpb:WU (Wistar random) rats. Data were collected from ten 24- to 30-month toxicity/carcinogenicity studies and from one 12-month study. Nasal tumors may lead to dyspnea, mouth breathing, and nasal discharge. These clinical signs mainly occurred in rats bearing squamous cell carcinomas. The large nasal tumors were often osteolytic, they inva...

back ground: the aim of this study was to characterize the immunohistochemical expression of galectin 1, 3, and 9 in normal oral epithelium, oral squamous papilloma, and oral squamous cell carcinoma. materials and methods: immunohistochemical staining for galectins 1, 3, and 9 was evaluated in 8 samples of normal oral squamous epithelium, 15 samples of oral squamous papilloma, and 41 samples of...

OBJECTIVES/HYPOTHESIS We aimed to determine the microRNA-21 expression in laryngeal squamous cell carcinoma and assess the association between the disease and clinical characteristics of patients. STUDY DESIGN Retrospective case-control study. METHODS A retrospective study was conducted from January 2005 to May 2011, in a tertiary hospital following tumor resection in 72 patients with laryn...

Laryngeal squamous cell carcinoma (SCC) is strongly linked to cigarette smoking. It is estimated to account for more than 70% of laryngeal SCCs and up to 89% in combination with alcohol. We wished to determine the prevalence of cigarette smoking and alcohol ingestion among patients with laryngeal squamous cell carcinoma and estimate risk attributed to cigarette smoking and alcohol ingestion. Fi...

BACKGROUND. Even if it is a rare variant growth pattern of squamous cell carcinoma, sarcomatoid carcinoma seems to have almost the same clinical manifestations and risk factors as conventional squamous cell carcinoma. CASE REPORT. This paper presents a complex case of a 59-year-old female patient known with laryngeal papillomatosis, who presented in our Department for moderate to severe inspira...

background: oral cancer is among the 10 most common cancers worldwide with an increasing global incidence. compromised antioxidant defense system plays a role in occurrence of cancer. this study evaluated the salivary antioxidant level of oral cancer patients compared to a control group. patients and methods: this case-control study was conducted on 22 oral squamous cell carcinoma patients pres...

conclusions according to the low prevalence of hcmv in oscc, it seems that this virus plays a minor role in this kind of cancer at least in southeast of iran. more comprehensive studies are needed to investigate the oncomodulatory effect of this virus on oscc. results the mean age of the patients (66.7% female and 33.3% male) was 58.6 years. only three cases (6.3%) of the grade i, oscc biopsies...

background:non-melanoma skin cancer (nmsc), the most prevalent types being squamous cell carcinoma (scc) and basal cell carcinoma (bcc), is the most common type of malignancy in human beings. these neoplasms are more frequent in the elderly and fair skinned people and mainly occur on sun-exposed sites of the body. ultraviolet b (uvb) has a well-known effect in induction and promotion of growth ...

abstract background and aim: oral cancer is one of the most common cancers of the head and neck. considering the high prevalence and mortality percentage of oral cancer and the significant advances in immunology and identification of different cytokines, the aim of the present study was to compare the concentration of il8 in saliva of patients with oral squamous cell carcinoma (oscc) and health...

squamous cell carcinoma, a cancer of keratinocytes origin, mostly involves sun-exposed areas of the skin. to study the pathologic and demographic features of this disease, records of 395 patients of squamous cell carcinoma of skin and lip were reviewed. most of the patients (83%) aged 40 years or more at the time of diagnosis. respectively, 74.4% and 75.8% of cases with skin and lower lip carci...