Journal of Refractive Surgery Volume 17 May/June 2001 ABSTRACT PURPOSE: To review the etiology, prevention, and management of laser in situ keratomileusis (LASIK) complications. METHODS: Review of literature and the experience of the authors. RESULTS: Careful preoperative screening is critical to prevention of many potential complications of LASIK. Flap complications that occur during surgery a...

The history of refractive eye surgery is recent, but has seen rapid advancement. Older technologies, such as radial keratectomy, had the problem of overcorrection and epithelial complications. Newer technologies, such as photorefractive keratectomy, laser-assisted in-situ keratomileusis (LASIK) and laser-assisted subepithelial keratomileusis (LASEK), which require the use of laser, has revoluti...

BACKGROUND/AIMS The biochemical basis for the development of subepithelial opacity of the cornea after excimer laser keratectomy has yet to be fully defined. The aim of this study was to evaluate the alterations of glycosaminoglycans (GAGs) after excimer laser keratectomy. METHODS Rabbit corneas were harvested on days 5, 10, 20, and 30 after excimer laser photoablation. The amount of main dis...

PURPOSE To compare the long-term refractive outcomes and changes in higher order wavefront aberrations in patients undergoing photorefractive keratectomy (PRK) with topography-guided (CATz) or wavefront-guided (OPDCAT) ablation algorithm using the NIDEK Advanced Vision Excimer Laser System (NAVEX). METHODS A retrospective 12-month follow-up study was conducted of 226 eyes undergoing PRK. The ...

1. Majmudar PA, Raviv T, Dennis RF, Epstein RJ. Subepithelial fibrosis after RK. J Cataract Refract Surg. 2000;26:1433-1434. 2. Fong YC, Chuck RS, Stark WJ, McDonnell PJ. Phototherapeutic keratectomy for superficial corneal fibrosis after radial keratotomy. J Cataract Refract Surg. 2000;26:616-619. 3. Majmudar PA, Forstot SL, Dennis RF, et al. Topical mitomycin-C for subepithelial fibrosis afte...

1. Majmudar PA, Raviv T, Dennis RF, Epstein RJ. Subepithelial fibrosis after RK. J Cataract Refract Surg. 2000;26:1433-1434. 2. Fong YC, Chuck RS, Stark WJ, McDonnell PJ. Phototherapeutic keratectomy for superficial corneal fibrosis after radial keratotomy. J Cataract Refract Surg. 2000;26:616-619. 3. Majmudar PA, Forstot SL, Dennis RF, et al. Topical mitomycin-C for subepithelial fibrosis afte...

This is a report of two brothers who underwent bilateral photorefractive keratectomy and developed bilateral peripheral corneal infiltrate on the third day following surgery. The patients were treated with antibiotics and low concentration steroid until negative culture was reported 48 h later, when intensive topical steroid was started. The infiltrate resolved by day 10 with residual subepithe...

BACKGROUND It is unclear whether a laser epithelial keratomileusis (LASEK) has any significant advantage over a photorefractive keratectomy (PRK) for correcting myopia. We undertook this meta-analysis of randomized controlled trials to examine possible differences in efficacy, accuracy, safety and side-effects between two methods, LASEK and PRK, for correcting myopia. METHODS A systematic lit...

PURPOSE To assess the efficacy and safety of topography-guided photorefractive keratectomy (PRK) for keratoconus and to estimate the subsequent risk of progression. METHODS This is a retrospective follow-up study. Between 1998 and 2013, 28 eyes of 23 patients (age 17-60) with grade 1-3 keratoconus received topography-guided PRK. Corrected-distance visual acuity (CDVA), keratometry, pachymetry...

PURPOSE To introduce an image analysis of the cornea in photorefractive keratectomy (PRK) for preoperative and early postoperative determination of changes in the condition of the cornea. METHODS Slit-lamp videography was used to evaluate the cornea. Microdensitometry of the corneal images was performed. The optic density of the anterior, middle, and posterior corneal layers was measured. Pho...