Background: Late onset neutropenia (neutropenia after 3 weeks of life) may be a physiological condition without need to prescribe antibiotics, G-CSF, or IVIG. We aimed to determine the association between sepsis and late onset neutropenia in very low birth weight (<1500 gm) infants.&nbsp; Methods: This study was a cross-sectional prospective study in VLBW infants that were admitted in Mahdieh ...

BACKGROUND Without neonatal initiation of treatment, 80-90% of patients with glutaric aciduria type 1 (GA1) develop striatal injury during the first six years of life resulting in a complex, predominantly dystonic movement disorder. Onset of motor symptoms may be acute following encephalopathic crisis or insidious without apparent crisis. Additionally, so-called late-onset GA1 has been describe...

Juvenile xanthogranuloma (JXG) is an uncommon histiocytic cutaneous lesion. It is a type of non-Langerhans cell histiocytosis(WHO Class IIb). The mean age of onset is 2 years of age. The adult form of JXG is relatively rare. The most common affectedarea is the face or the scalp and most of the lesions are less than 5 mm in diameter. This lesion tends to show a self-limited course over several m...

A 93-year-old lady developed extensive skin lesions following treatment with ciprofloxacin for urinary tract infection. Skin biopsy confirmed toxic epidermal necrolysis. She died within 48 hours of onset of her skin signs in spite of active management. Toxic epidermal necrolysis is a rare but serious side-effect of ciprofloxacin.

The case, who discribed here is a 66-year-old man with one year history of asymptomatic, keratotic papules with a linear distribution on the skin of his right palm near the wrist. On histopathological examination cornoid lamella-like parakeratotic columns above eccrine sweat ducts were observed. The acrosyringium was also dilated. He had been followed up for predominantly sensory polyneur...

Pyoderma gangrenosum is a rare neutrophilic dermatosis characterized by painful, rapidly progressing necrotic ulcers. Although PG has been reported in association with various autoimmune diseases, its coexistence rheumatoid arthritis (RA) mimicking vasculitis uncommon. We present case report of 75-year-old female longstanding history RA who developed ulcerative skin lesions that initially prese...

BACKGROUND There is evidence for a vascular cause of late-life depression. Cerebral white matter lesions are thought to represent vascular abnormalities. White matter lesions have been related to affective disorders and a history of late-onset depression in psychiatric patients. Their relation with mood disturbances in the general population is not known. We investigated the relation between wh...

abstract background: mustard gas, lethal in high doses, affects multiple organs such as skin, eye and respiratory system. we studied the development of late onset mustardinduced polyneuropathy among chemically wounded iranian veterans. methods: in this descriptive study, 100 chemically wounded iranian veterans with severe eye involvement were examined for any signs and symptoms of polyneuropath...

We report an 82-year-old lady who developed sudden onset nodular and erythematous lesions and neutrophilia following an episode of urinary tract infection. Skin biopsy confirmed the diagnosis of Sweet syndrome. Response to the use of prednisolone alone was not satisfactory. The skin lesions however showed a sustained response to the regular use of intravenous immunoglobulin (IVIG) and prednisol...