introduction: orexin-a and b (hypocretin 1 and 2) are neuropeptides that are mostly expressed in the posterior and lateral hypothalamus (lh). intracisternal (icv) and intratechal (it) injections of orexin-a (hypocretin-1) have been shown to elicit analgesic responses in formalin test. however, the locations of central sites that may mediate these effects have not been clearly elucidated. orexin...

Many problems of distributed object-oriented applications can be uniformly resolved in the frame of approach based on the concept of cover. The cover is defined as an environment which transparently controls all aspects of object’s community life: creation, interaction etc. To enable transparency, an objectoriented application must obey a principle of late binding, a reference to server object ...

To date, there has been little research examining whether short-time changes of external environmental conditions exert any effects on immune responses. The activation of metabolic changes, release of hormones responsive for immunomodulation and the action of interleukins play an important role in interaction with hormones of an anterior pituitary gland in the proestrous phase of the reproducti...

We studied functional and morphological luteinization of granulosa cells in intact preovulatory follicles and in cultured granulosa cells collected from the proestrous follicles of the rat. Steroid hormones were measured by radioimmunoassay in follicles dissected from the ovaries every 2 hrs on the day of proestrus beginning at 8 : 00 hrs and terminating at the time of ovulation. Granulosa cell...

Introduction: Orexin-A and B (Hypocretin 1 and 2) are neuropeptides that are mostly expressed in the posterior and lateral hypothalamus (LH). Intracisternal (ICV) and intratechal (IT) injections of orexin-A (hypocretin-1) have been shown to elicit analgesic responses in formalin test. However, the locations of central sites that may mediate these effects have not been clearly elucidated. Ore...

the chemical composition, ruminal degradability parameters, ruminal and post ruminal digestibility of saffron residues were determined using in situ and in vitro (gas production) methods. the harvested residues at late vegetative phase were compared with the residues harvested at the early dormant phase. the results showed that ndf and adf concentration of harvested residues at early dormant ph...

cows 2 weeks after parturition and in diestrous and proestrous heifers. Serum LH concentrations increased after LH-RH treatment and the greatest response was observed in cows with ovarian follicular cysts. Serum progesterone concentrations were increased at 6 hours after LH-RH in animals which had functional luteal tissue in the ovaries but serum estradiol and estrone were unchanged. Ovarian fo...

Estrogen receptor (ER)beta is present in hypothalamic and limbic neurons of female rat brains, but little is known about its regulation under physiological conditions. To determine whether ER beta expression varies during physiological conditions in which sex steroid hormone profiles are significantly different, we used in situ hybridization to assess ER beta mRNA expression in the periventricu...

Oestrous cycle and sex differences in sodium-dependent transport of L-[3H]glutamate and L-[3H]aspartate were investigated employing well washed synaptosomes prepared from rat brain cortex. Transport was best analysed on the basis of two components, a high and low affinity transport site. Oestrous cycle and sex differences were observed for both substrates. The high affinity transporter displaye...