bstract—Most gap junctions between neurons in mammaian retina contain abundant connexin36, often in association ith the scaffolding protein zonula occludens-1. We now nvestigate co-association of connexin36, zonula occludens-1, onula occludens-2 and Y-box transcription factor 3 (zonula ccludens-1-associated nucleic acid-binding protein) in ouse and rat retina. By immunoblotting, zonula occluden...

lysozyme is one of the bioactive components of eggs with well known antibacterial potential, widely used in food industry, medicine and pharmaceutics. in this study, the possibility of quail’s egg lysozyme concentration and activity (modified via amino acids dietary supplementation) was investigated. in accordance with lysozyme amino acids profile, four amino acids of: asparagine, arginine, gly...

mefloquine (mfq), as a racemic mixture is used for the prophylaxis and treatment of malaria. stereoselective pharmacodynamic and pharmacokinetic differences have been observed for mfq. in the present study, the human blood was spiked with racemic mfq. the concentration of mfq enantiomers in various blood fractions including packed erythrocyte layer, platelet rich plasma and platelet poor plasma...

Crystalline arrays of proteinaceous subunits forming surface layers (S-layers) are now recognized as one of the most common outermost cell envelope components of prokaryotic organisms. The surface layer protein of Lactobacillus acidophilus ATCC4356 is composed of a single species of protein of apparent molecular weight of 43-46 KDa. Considering the Lactobacillus acidophilus ATCC4356 having the ...

The cell surface of Aeromonas salmonicida is covered by a regular surface array composed of a single species of protein, the A-protein (Phipps, B. M., Trust, T. J., Ishiguro, E. E., and Kay, W. W. (1983) Biochemistry 22, 2934-2939). The array, known as the A-layer, is the key virulence factor for this organism. Cells containing the A-layer specifically bound rabbit IgG and human IgM with high a...

Multidrug regimens can sometimes treat recalcitrant diseases when single-drug therapies fail. Recapitulating complex multidrug administration from controlled release films for localized delivery remains challenging because their release kinetics are frequently intertwined, and an initial burst release of each drug is usually uncontrollable. Kinetic control over protein release is demonstrated b...

due to the need to find new protein sources with considering the fact that the bitter vetch seed has high levels of protein content, physicochemical and mechanical properties of bitter vetch seed and functional properties of its flour were evaluated in this study. the effects of altering the ph on protein solubility, foaming capacity, foaming stability, emulsion capacity and emulsion stability ...