The hepato protective effect of the methanolic extract of Pongamia Pinnata flowers, an indigenous. Ayurvedic medicinal plant in India, was studied in rats with lead acetate induced hepatotoxicity. Administering 160 mg/kg b.wt/day of lead acetate for 90 days to male albino rats resulted in significantly elevated levels of ALT, AST, GGT, ALP, Bilirubin and protein were also observed on lead aceta...

Estradiol (E2) is suppressed in prepubertal females exposed maternally to lead (Pb); thus, we assessed effects of Pb on ovarian steroidogenic acute regulatory protein (StAR) as a potential mechanism for this action. Adult Fisher 344 females were dosed with 12 mg of lead acetate per ml of Pb acetate (PbAc) or sodium acetate (NaAc; control), beginning 30 days prior to breeding and continuing unti...

BACKGROUND In the present study, the oral effect of lead acetate on the parameters related to sexual behavior as well as changes in the level of testosterone hormone in adult male rats have been investigated. MATERIALS AND METHODS Forty adult male Wistar rats were allocated into five equal groups. The control group received nothing, the sham group received distilled water and the experimental...

most serious problem that leads to reproductive system failure in both human and animals. Present study was carried out to investigate whether hydroalcholic extract of Dorema aucheri leaves could protect the male rats against lead-induced reproductive toxicity. Materials and Methods: Adult wistar rats were treated with 0.1% lead acetate in drinking water with or without 100, 200 and 400 mg/kg D...