نتایج جستجو برای: lead compounds
تعداد نتایج: 555612 فیلتر نتایج به سال:
Human African trypanosomiasis (HAT) is a major tropical disease for which few drugs for treatment are available, driving the need for novel active compounds. Recently, morpholino-substituted benzyl amides of the fluoroquinolone-type antibiotics were identified to be compounds highly active against Trypanosoma brucei brucei Since the lead compound GHQ168 was challenged by poor water solubility i...
The Ocean, which is called the "mother of origin of life," is also the source of structurally unique natural products that are mainly accumulated in living organisms. Cyanobacteria are photosynthetic prokaryotes used as food by humans. They are excellent source of vitamins and proteins vital for life. Several of these compounds show pharmacological activities and are helpful for the invention a...
The effect of trialkyllead and trialkyltin on pig erythrocyte hemolysis has been studied and compared. The results of experiments showed that the hemolytic activity of organoleads increases with their hydrophobicity and follows the sequence: triethyllead chloride < tri-n-propyllead chloride < tributyllead chloride. And similarly in the case of organotins: triethyltin chloride < tri-n-propyltin ...
List of Abbreviations: EP: Ergosterol Peroxide; ERGO: Ergosterol; U266, RPMI-8226, PMI-8226: Multiple Myeloma cell Line; SNU-1: Human Gastric Tumor Cell Line; Hep3B, HepG2, SUN354, BEL-7402, LO2: Human Hepatoma Cell Line; SUN -C4: Human colorectal tumor cell line; HL60, K562, P388, K462: Human Leukaemia Cell Line; DU-145, LNCAP: Human Prostate Cancer Cell line; HT29, COLO-205: Human Colorectal ...
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