Schizophrenia: A Plausible Neurobiologic Connection In their article in the April issue of EHP, Opler et al. (2004) raise the intriguing possibility that prenatal exposure to the ubiquitous developmental neurotoxicant lead (Pb2+) may be associated with schizophrenia, an adult psychiatric disease. Although the study has certain limitations that the authors discussed, it brings to light the possi...

Long-term exposure to low levels of lead (Pb2+) has been shown to produce learning and memory deficits in rodents and humans. These deficits are thought to be associated with altered brain monoamine neurotransmission. Increased brain 5-HT (5-hydroxytryptamine; serotonin) activity is thought to be a prerequisite for maintaining control over the cognitive information process, and is said to have ...

Heavy metal ions, lead, cadmium and nickel, are well known carcinogens with natural different origins and their direct mode of action is still not fully understood. A dsDNA-electrochemical biosensor, employing differential pulse voltammetry, was used for the in situ evaluation of Pb2+, Cd2+ and Ni2+ interaction with dsDNA. The results confirm that Pb2+, Cd2+ and Ni2+ bind to dsDNA, and that thi...

steel slags are the by products of steel industries, which forms during reduction process of iron melting. the chemical composition of it changes depending to the melting procedure. its mineralogical composition also varies based on the cooling procedure. two different types of steel slag were used as absorbing bed for various concentrations of pb2+ ions in the form of lead chloride, and the co...

Schizophrenia: A Plausible Neurobiologic Connection In their article in the April issue of EHP, Opler et al. (2004) raise the intriguing possibility that prenatal exposure to the ubiquitous developmental neurotoxicant lead (Pb2+) may be associated with schizophrenia, an adult psychiatric disease. Although the study has certain limitations that the authors discussed, it brings to light the possi...

The widespread occurrence of soil Pb contamination requires a good understanding of the factors controlling Pb solubility. Pb solubility will often be controlled by phosphates, which are used to reduce environmental risks of Pb-contaminated soils. The solubility equilibria of two different synthetic lead phosphate minerals were determined electrochemically across a wide range of pH and Pb and p...

The dinuclear title compound, [Pb(2)(C(6)H(8)O(4))(NO(3))(2)(C(19)H(13)N(5))(2)], lies with the mid-point of the butyl chain of the bridging adipate unit on a center of inversion. The Pb(II) ion is covalently bonded to the nitrate anion and is bonded to a carboxyl-ate group of the adipate unit by another covalent bond. The N-heterocycle functions in a chelating tridentate mode. The metal atom e...

The reaction of lead(II) acetate and 3-methyl-benzoic acid (MBA) in aqueous solution yielded the title polymer, [Pb(C(8)H(7)O(2))(2)(H(2)O)](n). The asymmetric unit contains two Pb(II) atoms, four MBA ligands and two water mol-ecules. Each Pb(II) cation is hepta-coordinated and chelated by four carboxyl-ate O atoms from two MBA ligands. The Pb atoms are bridged through the carboxyl-ate O atoms ...

Bacterial surface adsorption reactions are influenced by electric field effects caused by changes in ionic strength; however, existing datasets are too sparse to definitively constrain these differences or to determine the best way to account for them using thermodynamic models. In this study, we examine the ionic strength dependence of proton and metal adsorption onto the surfaces of Pseudomon...