BACKGROUND Patients treated with nasal continuous positive airway pressure (nasal CPAP) for obstructive sleep apnea (OSA) often have adverse effects from and poor adherence to CPAP. OBJECTIVE To describe abnormal CPAP leak profiles and assess inter-observer reliability in identifying leak profiles and the correlation of leak profiles with leak rate and clinical outcomes. METHODS In a sleep-...

Magnetic skyrmions are nanoscale magnetic whirls that highly stable and can be moved by currents which has led to the prediction of a skyrmion-based artificial neuron device with leak-integrate-fire functionality. However, so far, these devices lack refractory process, estimated crucial for neuronal dynamics. Here we demonstrate biskyrmion-based overcomes this insufficiency. When driven spin-or...

a majority of people, asked a simple yes/no question, were indeed opposed to the creation of animalhuman hybrids. However (in line with similar surveys on animal experimentation) support for the procedure rose to 61 per cent when the potential benefits of the work were explained. Announcing the eventual decision in September, the HFEA emphasised the importance of this public support – which res...

BACKGROUND During noninvasive ventilation (NIV), leak around the mask may cause inadequate ventilatory support or patient-ventilator asynchrony such as auto-triggering. Some NIV ventilators may be better than others at compensating for leak. METHODS We bench studied 3 NIV ventilators (Vision, Carina, and Trilogy100) and 2 ICU ventilators (Puritan Bennett 840 and Evita XL) to assess how they ...

BACKGROUND Prosthetic valve leak is a possible complication of surgical valve replacement. Although uncommon, its consequences may be serious. Few studies correlate the degree of prosthetic valve leak with clinical events. OBJECTIVE To compare the postoperative outcome of patients with mild/moderate (Mi/Mo) or severe (Sev) prosthetic valve leak METHODS A total of 185 patients with prostheti...

 Background: Proposing a strategy for sellar reconstruction in endoscopic transsphenoidal transsellar approach for pituitary adenoma. Methods: 240 patients with pituitary adenoma underwent pure endoscopic endonasal transsphenoidal surgery. Intra-operative CSF leaks were classified as grade 0, no observable leak grade 1, CSF dripping through an arachnoid membrane defect of less than 1 ...

This article presents different types of commercially available roof waterproofing membrane systems used on roofs with large surface area. It deals the causes deterioration such membranes due to environmental factors and describes tests detect leaks determination severity polymeric taking into account properties declared by their manufactures. The last part is a case study comparing brand new a...

The efficient use of water resources is a subject of major concern for water utilities and authorities. One of the main challenges in improving the efficiency of drinking water networks is to minimize water loss in pipes due to leakage. Water leaks in water distribution networks are unavoidable. They can cause significant economic losses in fluid transportation and an increase on reparation cos...

Background: CSF leak during or after transsphenoidal surgery is the most common annoying complication that may lead to fatal meningitis. Objective: To define the effectiveness of the external CSF lumbar drain to stop the leak either inserted preoperative, immediate postoperative or delayed postoperative with the same figure of packing to the sella turcica and sphenoid sinus. Methods: We retrosp...

Objective: To evaluate the efficacy of a simple method to minimize gastric inflation in unprotected airways during resuscitation procedures. Methods: Ventilation of an airway simulator by use of a hose extended mask with leak and without leak and with or without additional oxygen (15 litres per minute). Experimental settings with artificial lung at a compliance = 300ml/ kPa and resistance = 0,5...