CONTEXT Patellofemoral pain syndrome (PFPS) is one of the most common overuse injuries. OBJECTIVE To assess the collective evidence of predisposing factors to PFPS. DATA SOURCES MEDLINE (1960-June 2010), EMBASE (1980-June 2010), and CINAHL (1982-June 2010). STUDY SELECTION Studies were included if patients were asymptomatic at baseline testing (free of PFPS) and were prospectively followe...

Weight-control behaviour is commonly observed in a wide range of elite sports, especially leanness sports, where control over body weight is crucial for high peak performance. Nonetheless, there is only a fine line between purely functional behaviour and clinically relevant eating disorders. Especially the rapid form of weight manipulation seems to foster later eating disorders. So far, most st...

Prader-Willi syndrome (PWS), a neurodevelopmental disorder caused by loss of paternal gene expression from 15q11-q13, is characterised by growth retardation, hyperphagia and obesity. However, as single gene mutation mouse models for this condition display an incomplete spectrum of the PWS phenotype, we have characterised the metabolic impairment in a mouse model for 'full' PWS, in which deletio...

OBJECTIVE To examine the BMI-stratified associations between diabetes and the risks of all-cause death, cardiovascular disease (CVD) death, and cancer death. RESEARCH DESIGN AND METHODS Using a prospective study with 12 rural Japanese general populations (n = 3,641, mean age, 53.7 years; 33.5% men), we examined the associations between diabetes and the risk of all-cause death, CVD death, and ...

OBJECTIVES This paper examines the influence of cigarette smoking and ill health on the relationship between weight change, body weight and subsequent mortality to determine whether weight loss and leanness in middle to older age is deleterious to health. METHODS Men aged 40-59 years at screening drawn from one general practice in each of 24 British towns, who completed a questionnaire 5 year...

last rib backfat thickness, broken vertebrae, or scores for stomach ulcers (P > 0.21). Also, deletions of VTM premixes did not affect these same measurements (P > 0.22). However, RAC decreased (P < 0.01) backfat thickness by 8% and tended to decrease scores for stomach ulcers (P < 0.06). In conclusion, there were no interactions to suggest that the effects of RAC on growth performance and carca...